PA1621
antibody from Boster Biological Technology
Targeting: ITGA3
CD49c, GAP-B3, MSK18, VCA-2, VLA3a
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PA1621 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Integrin alpha 3/ITGA3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for Integrin alpha 3/ITGA3 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Integrin alpha 3/ITGA3 information: Molecular Weight: 116612 MW; Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor . Cell projection, invadopodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner; Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Iron/ROS/Itga3 mediated accelerated depletion of hippocampal neural stem cell pool contributes to cognitive impairment after hemorrhagic stroke.
Effect of Irisin on LIF and integrin αvβ3 in rats of implantation failure.
Synthesis and Preclinical Evaluation of a (68)Ga-Radiolabeled Peptide Targeting Very Late Antigen-3 for PET Imaging of Pancreatic Cancer.
Zhang X, Li H, Wang H, Zhang Q, Deng X, Zhang S, Wang L, Guo C, Zhao F, Yin Y, Zhou T, Zhong J, Feng H, Chen W, Zhang J, Feng H, Hu R
Redox biology 2024 May;71:103086
Redox biology 2024 May;71:103086
Effect of Irisin on LIF and integrin αvβ3 in rats of implantation failure.
Zhou L, Li C, Liu X, Zhang T
Reproductive biology and endocrinology : RB&E 2021 Feb 3;19(1):18
Reproductive biology and endocrinology : RB&E 2021 Feb 3;19(1):18
Synthesis and Preclinical Evaluation of a (68)Ga-Radiolabeled Peptide Targeting Very Late Antigen-3 for PET Imaging of Pancreatic Cancer.
Li H, Yuan L, Long Y, Fang H, Li M, Liu Q, Xia X, Qin C, Zhang Y, Lan X, Gai Y
Molecular pharmaceutics 2020 Aug 3;17(8):3000-3008
Molecular pharmaceutics 2020 Aug 3;17(8):3000-3008
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Integrin alpha 3 antibody, PA1621, Western blottingLane 1: Rat Heart Tissue LysateLane 2: HELA Cell Lysate
- Additional image