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Western blot
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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- HPA008572 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA008572, RRID:AB_2668094
- Product name
- Anti-ITGA3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ITGA3, Gene description: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor), Alternative Gene Names: CD49c, GAP-B3, MSK18, VCA-2, VLA3a, Validated applications: WB, IHC, Uniprot ID: P26006, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
Glomerular endothelial cell-podocyte stresses and crosstalk in structurally normal kidney transplants
High integrin α3 expression is associated with poor prognosis in patients with non-small cell lung cancer
Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs
Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer
Regulation of ITGA3 by the anti‐tumor miR‐199 family inhibits cancer cell migration and invasion in head and neck cancer
α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway
Tumor‐suppressive microRNA‐223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer
Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, Mahadevan K, Wu C, Sugimoto H, Chang C, Jenq R, McAndrews K, Kalluri R
Cancer Cell 2022;40(8):818-834.e9
Cancer Cell 2022;40(8):818-834.e9
Glomerular endothelial cell-podocyte stresses and crosstalk in structurally normal kidney transplants
Menon R, Otto E, Berthier C, Nair V, Farkash E, Hodgin J, Yang Y, Luo J, Woodside K, Zamani H, Norman S, Wiggins R, Kretzler M, Naik A
Kidney International 2022;101(4):779-792
Kidney International 2022;101(4):779-792
High integrin α3 expression is associated with poor prognosis in patients with non-small cell lung cancer
Li Q, Ma W, Chen S, Tian E, Wei S, Fan R, Wang T, Zhou C, Li T
Translational Lung Cancer Research 2020;9(4):1361-1378
Translational Lung Cancer Research 2020;9(4):1361-1378
Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs
Koshizuka K, Nohata N, Hanazawa T, Kikkawa N, Arai T, Okato A, Fukumoto I, Katada K, Okamoto Y, Seki N
Oncotarget 2017;8(18):30288-30304
Oncotarget 2017;8(18):30288-30304
Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer
Sakaguchi T, Yoshino H, Yonemori M, Miyamoto K, Sugita S, Matsushita R, Itesako T, Tatarano S, Nakagawa M, Enokida H
British Journal of Cancer 2017;116(8):1077-1087
British Journal of Cancer 2017;116(8):1077-1087
Regulation of ITGA3 by the anti‐tumor miR‐199 family inhibits cancer cell migration and invasion in head and neck cancer
Koshizuka K, Hanazawa T, Kikkawa N, Arai T, Okato A, Kurozumi A, Kato M, Katada K, Okamoto Y, Seki N
Cancer Science 2017;108(8):1681-1692
Cancer Science 2017;108(8):1681-1692
α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway
Varzavand A, Hacker W, Ma D, Gibson-Corley K, Hawayek M, Tayh O, Brown J, Henry M, Stipp C
Cancer Research 2016;76(22):6577-6587
Cancer Research 2016;76(22):6577-6587
Tumor‐suppressive microRNA‐223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer
Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, Sakamoto S, Enokida H, Nakagawa M, Ichikawa T, Seki N
Cancer Science 2015;107(1):84-94
Cancer Science 2015;107(1):84-94
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and ITGA3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY419471).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human lung and skeletal muscle tissues using HPA008572 antibody. Corresponding ITGA3 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
