Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- AF907 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal MMP-7 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human MMP-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse MMP-7 is observed, and less than 1% cross-reactivity with recombinant human (rh) MMP-8 and rhMMP-12 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer.
Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.
Determination of matrilysin activity in gastrointestinal neoplasia.
Peng Z, Chen J, Drachenberg CB, Raufman JP, Xie G
The Journal of biological chemistry 2019 May 24;294(21):8529-8542
The Journal of biological chemistry 2019 May 24;294(21):8529-8542
Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.
Zhuo J, Tan EH, Yan B, Tochhawng L, Jayapal M, Koh S, Tay HK, Maciver SK, Hooi SC, Salto-Tellez M, Kumar AP, Goh YC, Lim YC, Yap CT
PloS one 2012;7(8):e43594
PloS one 2012;7(8):e43594
Determination of matrilysin activity in gastrointestinal neoplasia.
Hawinkels LJ, Verspaget HW, van den Berg M, Hanemaaijer R, Sier CF
European journal of clinical investigation 2007 Jul;37(7):598-9
European journal of clinical investigation 2007 Jul;37(7):598-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human MMP-7 by Western Blot. Detection of Human MMP-7 by Western Blot.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human MMP-7 by Simple WesternTM. Detection of Human MMP-7 by Simple WesternTM.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- MMP-7 in Human Pancreas. MMP-7 in Human Pancreas.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Neutralization of MMP-7 Activity by Human MMP-7 Antibody. Neutralization of MMP-7 Activity by Human MMP-7 Antibody.