Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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Comment
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- Product number
- PAB4796 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4796, RRID:AB_1577368
- Product name
- MMP7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MMP7.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion.
Matrilysin-dependent elastolysis by human macrophages.
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.
Rivat C, Le Floch N, Sabbah M, Teyrol I, Redeuilh G, Bruyneel E, Mareel M, Matrisian LM, Crawford HC, Gespach C, Attoub S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Sep;17(12):1721-3
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Sep;17(12):1721-3
Matrilysin-dependent elastolysis by human macrophages.
Filippov S, Caras I, Murray R, Matrisian LM, Chapman HA Jr, Shapiro S, Weiss SJ
The Journal of experimental medicine 2003 Sep 15;198(6):925-35
The Journal of experimental medicine 2003 Sep 15;198(6):925-35
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.
Fu X, Kassim SY, Parks WC, Heinecke JW
The Journal of biological chemistry 2003 Aug 1;278(31):28403-9
The Journal of biological chemistry 2003 Aug 1;278(31):28403-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The MMP7 polyclonal antibody (Cat # PAB4796) is used in Western blot to detect MMP7 in 293 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with MMP7 polyclonal antibody (Cat # PAB4796) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)