Antibody data
- Antibody Data
- Antigen structure
- References [189]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10371-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10371-2-AP, RRID:AB_2297741
- Product name
- MMP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MMP1 antibody (Cat. #10371-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vocal fold fibroblasts and exposure to vibration in vitro: Does sex matter?
Programmed cell death-index (PCDi) as a prognostic biomarker and predictor of drug sensitivity in cervical cancer: a machine learning-based analysis of mRNA signatures.
Protective effects of sugarcane polyphenol against UV-B-induced photoaging in Balb/c mouse skin: Antioxidant, anti-inflammatory, and anti-glycosylation Effects.
Characterization of a novel rabbit model of Peyronie's disease.
Identification of Circulating Inflammatory Proteins Associated with Calcific Aortic Valve Stenosis by Multiplex Analysis.
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway.
Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1.
Establishment of a Mouse Degenerative Model of Patellar Tendinopathy with Upregulation of Inflammation.
The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics.
Dimethyl α-Ketoglutarate Promotes the Synthesis of Collagen and Inhibits Metalloproteinases in HaCaT Cells.
The mechanism of action of myricetin against lung adenocarcinoma based on bioinformatics, in silico and in vitro experiments.
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis.
The correlation between dermoscopy and clinical and pathological tests in the evaluation of skin photoaging.
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging.
Hesperetin activates CISD2 to attenuate senescence in human keratinocytes from an older person and rejuvenates naturally aged skin in mice.
The osteogenic effects of sappanchalcone in vitro and in vivo.
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Network Pharmacology and Experimental Verifications to Discover Scutellaria baicalensis Georgi's Effects on Joint Inflammation, Destruction, and Pain in Osteoarthritis.
Peroxiredoxin 3 regulates breast cancer progression via ERK-mediated MMP-1 expression.
Doxycycline hydrochloride inhibits the progress of malignant rhabdoid tumor of kidney by targeting MMP17 and MMP1 through PI3K-Akt signaling pathway.
Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway.
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats.
Mitochondria-related chemoradiotherapy resistance genes-based machine learning model associated with immune cell infiltration on the prognosis of esophageal cancer and its value in pan-cancer.
Ulipristal (UPA) effects on rat ovaries: Unraveling follicle dynamics, ovulation inhibition, and safety implications for prolonged use.
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Integrated Network Pharmacology and Experimental Approach to Investigate the Protective Effect of Jin Gu Lian Capsule on Rheumatoid Arthritis by Inhibiting Inflammation via IL-17/NF-κB Pathway.
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Dendrobium nobile Lindl Polysaccharides Attenuate UVB-induced Photodamage by Regulating Oxidative Stress, Inflammation and MMPs Expression in Mice Model.
Comparing Effects of Short- and Long-Term Exposure of Cigarette Smoke Extract on Human Vocal Fold Fibroblasts.
Microalgae Microneedle Supplies Oxygen for Antiphotoaging Treatment.
Research on Circular RNA Expression Profiles in the Photoaging Mouse Model.
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.
Protective effects of Cu/Zn-SOD and Mn-SOD on UVC radiation-induced damage in NIH/3T3 cells and murine skin.
Epithelial cells activate fibroblasts to promote esophageal cancer development.
Overexpression of TWF1 promotes lung adenocarcinoma progression and is associated with poor prognosis in cancer patients through the MMP1 signaling pathway.
Loss of AKAP12 aggravates rheumatoid arthritis-like symptoms and cardiac damage in collagen-induced arthritis mice.
Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases.
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway.
Albumin fusion with human lactoferrin shows enhanced inhibition of cancer cell migration.
Decreased CRISPLD2 expression impairs osteogenic differentiation of human mesenchymal stem cells during in vitro expansion.
Luteolin ameliorates cornea stromal collagen degradation and inflammatory damage in rats with corneal alkali burn.
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease.
Metastatic effects of environmental carcinogens mediated by MAPK and UPR pathways with an in vivo Drosophila Model.
COL8A1 enhances the invasion/metastasis in MDA-MB-231 cells via the induction of IL1B and MMP1 expression.
Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Anti-inflammation and anti-aging mechanisms of mercaptopurine in vivo and in vitro.
Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism.
Collagen-EGCG Combination Synergistically Prevents UVB-Induced Skin Photoaging in Nude Mice.
Bauhinia championii alleviates extracellular matrix degradation in IL-1β induced chondrocytes via miRNA-145-5p/TLR4/NF-κB axis.
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study.
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Interleukin-26 Expression in Inflammatory Bowel Disease and Its Immunoregulatory Effects on Macrophages.
Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment.
Network Pharmacology-Based Strategy to Investigate the Mechanisms of Cibotium barometz in Treating Osteoarthritis.
Repression of the Antioxidant Pyrroloquinoline Quinone in Skin Aging Induced by Bmi-1 Deficiency.
MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension.
Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2.
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
MMP1 acts as a potential regulator of tumor progression and dedifferentiation in papillary thyroid cancer.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF-κB pathway.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Belinostat (PXD101) resists UVB irradiation-induced cellular senescence and skin photoaging.
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Antioxidant, Anti-Inflammation and Antiaging Activities of Artocarpus altilis Methanolic Extract on Urban Particulate Matter-Induced HaCaT Keratinocytes Damage.
The miR-145-MMP1 axis is a critical regulator for imiquimod-induced cancer stemness and chemoresistance.
Effects of the Leptin-Mediated MAPK/ERK Signaling Pathway on Collagen II Expression in Knee Cartilage of Newborn Male Mice from Obese Maternal Offspring.
The Effects and Mechanisms of the Rapamycin-eluting Stent in Urethral Stricture Prevention in Rabbits.
Identity of MMP1 and its effects on tumor progression in head and neck squamous cell carcinoma.
Liposomes Encapsulating Morin: Investigation of Physicochemical Properties, Dermal Absorption Improvement and Anti-Aging Activity in PM-Induced Keratinocytes.
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway.
Allergy-induced systemic inflammation impairs tendon quality.
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes.
Effects of intra-articular inoculation with Mycoplasma bovis on immunological responses in calf joints.
S100A10 regulates tumor necrosis factor alpha-induced apoptosis in chondrocytes via the reactive oxygen species/nuclear factor-kappa B pathway.
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Ursolic acid alleviates Kupffer cells pyroptosis in liver fibrosis by the NOX2/NLRP3 inflammasome signaling pathway.
Circ_0011129 Encapsulated by the Small Extracellular Vesicles Derived from Human Stem Cells Ameliorate Skin Photoaging.
LncRNA HIF1A-AS1 Regulates the Cellular Function of HUVECs by Globally Regulating mRNA and miRNA Expression.
Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase.
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7.
Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways.
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes.
Oleanolic Acid Nanofibers Attenuated Particulate Matter-Induced Oxidative Stress in Keratinocytes.
Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model.
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Cold exposure and capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling.
High fibular osteotomy ameliorates medial compartment knee osteoarthritis in a rabbit model.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Novel histopathological classification of meningiomas based on dural invasion.
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally.
4-Hydroxy-7-oxo-5-heptenoic acid lactone is a potent inducer of brain cancer cell invasiveness that may contribute to the failure of anti-angiogenic therapies.
Intra-articular collagenase in the spinal facet joint induces pain, DRG neuron dysregulation and increased MMP-1 absent evidence of joint destruction.
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway.
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis.
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Tricetin Protects Rat Chondrocytes against IL-1β-Induced Inflammation and Apoptosis.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Concentration-Dependent Effects of Fibroblast-Like Synoviocytes on Collagen Gel Multiscale Biomechanics and Neuronal Signaling: Implications for Modeling Human Ligamentous Tissues.
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway.
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus.
Liraglutide alleviates cardiac fibrosis through inhibiting P4hα-1 expression in STZ-induced diabetic cardiomyopathy.
Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Isorhapontigenin Suppresses Interleukin-1β-Induced Inflammation and Cartilage Matrix Damage in Rat Chondrocytes.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model.
Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways.
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation.
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes.
Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis.
Cellular communication promotes mammosphere growth and collective invasion through microtubule‑like structures and angiogenesis.
Overexpression of matrix metalloproteinase-9 in adolescents with primary spontaneous pneumothorax for surgical intervention.
Tumor cell density regulates matrix metalloproteinases for enhanced migration.
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver.
Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation.
Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions.
MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN.
18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
The trophoblast plug during early pregnancy: a deeper insight.
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression.
Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells.
Potent effects of dioscin against liver fibrosis.
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2.
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.
Kirsch A, Grossmann T, Steffan B, Groselj-Strele A, Gerstenberger C, Gugatschka M
PloS one 2024;19(2):e0297168
PloS one 2024;19(2):e0297168
Programmed cell death-index (PCDi) as a prognostic biomarker and predictor of drug sensitivity in cervical cancer: a machine learning-based analysis of mRNA signatures.
Wang W, Chen P, Yuan S
Journal of Cancer 2024;15(5):1378-1396
Journal of Cancer 2024;15(5):1378-1396
Protective effects of sugarcane polyphenol against UV-B-induced photoaging in Balb/c mouse skin: Antioxidant, anti-inflammatory, and anti-glycosylation Effects.
Wang J, Wang M, Zhang C, Li W, Zhang T, Zhou Y, Flavel M, Xi Y, Li H, Liu X
Journal of food science 2024 May;89(5):3048-3063
Journal of food science 2024 May;89(5):3048-3063
Characterization of a novel rabbit model of Peyronie's disease.
Gundogdu G, Nguyen T, Namasivayam A, Starek S, Gelman J, Mauney JR
International journal of impotence research 2024 May;36(3):269-274
International journal of impotence research 2024 May;36(3):269-274
Identification of Circulating Inflammatory Proteins Associated with Calcific Aortic Valve Stenosis by Multiplex Analysis.
Lin R, Zhu Y, Chen W, Wang Z, Wang Y, Du J
Cardiovascular toxicology 2024 May;24(5):499-512
Cardiovascular toxicology 2024 May;24(5):499-512
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28
Military Medical Research 2024 May 6;11(1):28
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway.
Lu P, Li S, Zhang C, Jiang X, Xiang J, Xu H, Dong J, Wang K, Shi Y
European journal of histochemistry : EJH 2024 May 22;68(2)
European journal of histochemistry : EJH 2024 May 22;68(2)
Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1.
Rao S, He Z, Wang Z, Yin H, Hu X, Tan Y, Wan T, Zhu H, Luo Y, Wang X, Li H, Wang Z, Hu X, Hong C, Wang Y, Luo M, Du W, Qian Y, Tang S, Xie H, Chen C
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1166-1186
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1166-1186
Establishment of a Mouse Degenerative Model of Patellar Tendinopathy with Upregulation of Inflammation.
Lui PPY, Liang Z, Tan RM, Yung PSH
International journal of molecular sciences 2024 Mar 29;25(7)
International journal of molecular sciences 2024 Mar 29;25(7)
The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics.
Qu L, Ma X, Wang F
Life sciences 2024 Mar 15;341:122487
Life sciences 2024 Mar 15;341:122487
Dimethyl α-Ketoglutarate Promotes the Synthesis of Collagen and Inhibits Metalloproteinases in HaCaT Cells.
Yu BY, Eom DH, Kim HW, Jeong YJ, Keum YS
Biomolecules & therapeutics 2024 Mar 1;32(2):240-248
Biomolecules & therapeutics 2024 Mar 1;32(2):240-248
The mechanism of action of myricetin against lung adenocarcinoma based on bioinformatics, in silico and in vitro experiments.
Hao P, Zhang C, Bian H, Li Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4089-4104
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4089-4104
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
Yu J, Duan Y, Lu Q, Chen M, Ning F, Ye Y, Lu S, Ou D, Sha X, Gan X, Zhao M, Lash GE
Placenta 2024 Jun;151:48-58
Placenta 2024 Jun;151:48-58
Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis.
Meng X, Chen Z, Li T, Nie Z, Han H, Zhong S, Yin Z, Sun S, Xie J, Shen J, Xu X, Gao C, Ran L, Xu B, Xiang Z, Wang J, Sun P, Xin P, A X, Zhang C, Qiu G, Gao H, Bian Y, Xu M, Cao B, Li F, Zheng L, Zhang X, Xiao L
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jan;76(1):32-47
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jan;76(1):32-47
The correlation between dermoscopy and clinical and pathological tests in the evaluation of skin photoaging.
Zhao J, Zhang X, Tang Q, Bi Y, Yuan L, Yang B, Cai M, Zhang J, Deng D, Cao W
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Jan;30(1):e13578
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Jan;30(1):e13578
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Ma Q, Chen F, Liu Y, Wu K, Bu Z, Qiu C, Neamati N, Lu T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging.
Ge Y, Li M, Bai S, Chen C, Zhang S, Cheng J, Wang X
International immunopharmacology 2024 Jan 25;127:111357
International immunopharmacology 2024 Jan 25;127:111357
Hesperetin activates CISD2 to attenuate senescence in human keratinocytes from an older person and rejuvenates naturally aged skin in mice.
Shen ZQ, Chang CY, Yeh CH, Lu CK, Hung HC, Wang TW, Wu KS, Tung CY, Tsai TF
Journal of biomedical science 2024 Jan 23;31(1):15
Journal of biomedical science 2024 Jan 23;31(1):15
The osteogenic effects of sappanchalcone in vitro and in vivo.
Zheng X, Chen J, Liu J, Shi X, Li G, Shi Q, Zhang J, Li Y
Journal of periodontal research 2024 Feb;59(1):84-93
Journal of periodontal research 2024 Feb;59(1):84-93
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Wu X, Zhang F, Mao X, Xu F, Ding X, Sun X, Wang J
Materials today. Bio 2024 Feb;24:100910
Materials today. Bio 2024 Feb;24:100910
Network Pharmacology and Experimental Verifications to Discover Scutellaria baicalensis Georgi's Effects on Joint Inflammation, Destruction, and Pain in Osteoarthritis.
Jo HG, Baek CY, Song HS, Lee D
International journal of molecular sciences 2024 Feb 9;25(4)
International journal of molecular sciences 2024 Feb 9;25(4)
Peroxiredoxin 3 regulates breast cancer progression via ERK-mediated MMP-1 expression.
Chua PJ, Ow SH, Ng CT, Huang WH, Low JT, Tan PH, Chan MWY, Bay BH
Cancer cell international 2024 Feb 6;24(1):59
Cancer cell international 2024 Feb 6;24(1):59
Doxycycline hydrochloride inhibits the progress of malignant rhabdoid tumor of kidney by targeting MMP17 and MMP1 through PI3K-Akt signaling pathway.
Mi T, Zhang Z, Zhanghuang C, Jin L, Tan X, Liu J, Wu X, Li M, Wang J, Wang Z, Guo P, He D
European journal of pharmacology 2024 Feb 5;964:176291
European journal of pharmacology 2024 Feb 5;964:176291
Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway.
Xia Y, Zhang H, Wu X, Xu Y, Tan Q
Biogerontology 2024 Aug;25(4):649-664
Biogerontology 2024 Aug;25(4):649-664
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Zhou S, Guo L, Cui X, Zhang X, Yang Y, Zhang M, Zhang P
Cellular signalling 2024 Aug;120:111217
Cellular signalling 2024 Aug;120:111217
Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats.
Jing SZ, Yang SH, Qu YK, Hao HH, Wu H
Current medical science 2024 Apr;44(2):355-368
Current medical science 2024 Apr;44(2):355-368
Mitochondria-related chemoradiotherapy resistance genes-based machine learning model associated with immune cell infiltration on the prognosis of esophageal cancer and its value in pan-cancer.
Liu Z, Zeinalzadeh Z, Huang T, Han Y, Peng L, Wang D, Zhou Z, Ousmane D, Wang J
Translational oncology 2024 Apr;42:101896
Translational oncology 2024 Apr;42:101896
Ulipristal (UPA) effects on rat ovaries: Unraveling follicle dynamics, ovulation inhibition, and safety implications for prolonged use.
Hirano M, Wada-Hiraike O, Fukui M, Shibata S, Uehara M, Nagumo A, Urata Y, Sone K, Harada M, Koga K, Osuga Y
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108571
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108571
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
Chen D, Cai B, Zhu Y, Ma Y, Yu X, Xiong J, Shen J, Tie W, Zhang Y, Guo F
Clinical epigenetics 2024 Apr 4;16(1):51
Clinical epigenetics 2024 Apr 4;16(1):51
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Dong Y, Zhang Y, Li F, Tang B, Lv D, Wang H, Luo S
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Integrated Network Pharmacology and Experimental Approach to Investigate the Protective Effect of Jin Gu Lian Capsule on Rheumatoid Arthritis by Inhibiting Inflammation via IL-17/NF-κB Pathway.
Chen T, Li S, Lian D, Hu Q, Hou H, Niu D, Li H, Song L, Gao Y, Chen Y, Hu X, Li J, Ye Z, Peng B, Zhang G
Drug design, development and therapy 2023;17:3723-3748
Drug design, development and therapy 2023;17:3723-3748
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Qu Y, Qiu L, Qiu H, Shen Y, Tang M, Huang Y, Peng Y, Wang J, Fu Q
Cytokine 2023 Sep;169:156309
Cytokine 2023 Sep;169:156309
Dendrobium nobile Lindl Polysaccharides Attenuate UVB-induced Photodamage by Regulating Oxidative Stress, Inflammation and MMPs Expression in Mice Model.
Long Y, Wang W, Zhang Y, Zhang S, Li Z, Deng J, Li J
Photochemistry and photobiology 2023 Sep-Oct;99(5):1269-1281
Photochemistry and photobiology 2023 Sep-Oct;99(5):1269-1281
Comparing Effects of Short- and Long-Term Exposure of Cigarette Smoke Extract on Human Vocal Fold Fibroblasts.
Steffan B, Grossmann T, Grill M, Kirsch A, Groselj-Strele A, Gugatschka M
Journal of voice : official journal of the Voice Foundation 2023 Sep 9;
Journal of voice : official journal of the Voice Foundation 2023 Sep 9;
Microalgae Microneedle Supplies Oxygen for Antiphotoaging Treatment.
Wang Z, Kwong CHT, Zhao H, Ding YF, Gao C, Zhang D, Cheng Q, Wei J, Zhang QW, Wang R
ACS applied bio materials 2023 Sep 18;6(9):3463-3471
ACS applied bio materials 2023 Sep 18;6(9):3463-3471
Research on Circular RNA Expression Profiles in the Photoaging Mouse Model.
Li Q, Lin M, Xie Y, Zhang J, Lai W
Iranian journal of biotechnology 2023 Oct;21(4):e3445
Iranian journal of biotechnology 2023 Oct;21(4):e3445
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Sun W, Yue J, Xu T, Cui Y, Huang D, Shi H, Xiong J, Sun W, Yi Q
Heliyon 2023 Nov;9(11):e21282
Heliyon 2023 Nov;9(11):e21282
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.
Zhang H, Xiang X, Zhou B, Chen J, Sun Y, Zhang S, Li A, Li J
Journal of biochemical and molecular toxicology 2023 May;37(5):e23306
Journal of biochemical and molecular toxicology 2023 May;37(5):e23306
Protective effects of Cu/Zn-SOD and Mn-SOD on UVC radiation-induced damage in NIH/3T3 cells and murine skin.
Chen D, Ai X, Li Y, Li Y, Ao Y, Rong J, Li G
Acta histochemica 2023 May;125(4):152030
Acta histochemica 2023 May;125(4):152030
Epithelial cells activate fibroblasts to promote esophageal cancer development.
Chen Y, Zhu S, Liu T, Zhang S, Lu J, Fan W, Lin L, Xiang T, Yang J, Zhao X, Xi Y, Ma Y, Cheng G, Lin D, Wu C
Cancer cell 2023 May 8;41(5):903-918.e8
Cancer cell 2023 May 8;41(5):903-918.e8
Overexpression of TWF1 promotes lung adenocarcinoma progression and is associated with poor prognosis in cancer patients through the MMP1 signaling pathway.
Zhai K, Jiang N, Wen JF, Zhang X, Liu T, Long KJ, Ke XX, Xu G, Chen C
Journal of thoracic disease 2023 May 30;15(5):2644-2658
Journal of thoracic disease 2023 May 30;15(5):2644-2658
Loss of AKAP12 aggravates rheumatoid arthritis-like symptoms and cardiac damage in collagen-induced arthritis mice.
Ni Y, Cao J, Yuan J, Ning X
Experimental animals 2023 May 17;72(2):242-252
Experimental animals 2023 May 17;72(2):242-252
Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases.
Chuang KC, Lai YW, Ko CH, Yen CC, Chen HL, Lan YW, Chen CF, Chen W, Chen CM
Life sciences 2023 Mar 15;317:121411
Life sciences 2023 Mar 15;317:121411
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Zhang T, Wang Y, Li R, Xin J, Zheng Z, Zhang X, Xiao C, Zhang S
Acta biomaterialia 2023 Mar 1;158:475-492
Acta biomaterialia 2023 Mar 1;158:475-492
PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway.
Qiu J, Feng M, Yang G, Su D, Zhao F, Liu Y, Tao J, Luo W, Zhang T
Heliyon 2023 Jun;9(6):e17194
Heliyon 2023 Jun;9(6):e17194
Albumin fusion with human lactoferrin shows enhanced inhibition of cancer cell migration.
Nopia H, Kurimoto D, Sato A
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2023 Jun;36(3):629-638
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2023 Jun;36(3):629-638
Decreased CRISPLD2 expression impairs osteogenic differentiation of human mesenchymal stem cells during in vitro expansion.
Rong W, Rome CP, Dietrich MA, Yao S
Journal of cellular physiology 2023 Jun;238(6):1368-1380
Journal of cellular physiology 2023 Jun;238(6):1368-1380
Luteolin ameliorates cornea stromal collagen degradation and inflammatory damage in rats with corneal alkali burn.
Wang H, Guo Z, Liu P, Yang X, Li Y, Lin Y, Zhao X, Liu Y
Experimental eye research 2023 Jun;231:109466
Experimental eye research 2023 Jun;231:109466
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Jiang L, Liu Y, Pan Y, Tan Z, Wang J, Zheng G, Qian C, Xu S, Zhu X, Ma W, Guerrini S, Infante-Cossio P, Wu J, Ge M, Cai X
Gland surgery 2023 Jun 30;12(6):834-852
Gland surgery 2023 Jun 30;12(6):834-852
Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease.
Fountoulakis N, Psefteli PM, Maltese G, Gnudi L, Siow RC, Karalliedde J
Kidney international reports 2023 Jul;8(7):1380-1388
Kidney international reports 2023 Jul;8(7):1380-1388
Metastatic effects of environmental carcinogens mediated by MAPK and UPR pathways with an in vivo Drosophila Model.
Fangninou FF, Yu Z, Li Z, Guadie A, Li W, Xue L, Yin D
Journal of hazardous materials 2023 Jan 5;441:129826
Journal of hazardous materials 2023 Jan 5;441:129826
COL8A1 enhances the invasion/metastasis in MDA-MB-231 cells via the induction of IL1B and MMP1 expression.
Sagara A, Miura S, Kobinata A, Naganawa R, Yaginuma S, Saito S, Saito R, Kominato H, Yumoto T, Sato F
Biochemical and biophysical research communications 2023 Jan 29;642:145-153
Biochemical and biophysical research communications 2023 Jan 29;642:145-153
Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.
Yi E, Cao W, Zhang J, Lin B, Wang Z, Wang X, Bai G, Mei X, Xie C, Jin J, Liu X, Li H, Wu F, Lin Z, Sun R, Li B, Zhou Y, Ran P
Life sciences 2023 Jan 15;313:121214
Life sciences 2023 Jan 15;313:121214
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB
Cell death & disease 2023 Jan 13;14(1):26
Cell death & disease 2023 Jan 13;14(1):26
Anti-inflammation and anti-aging mechanisms of mercaptopurine in vivo and in vitro.
Jia H, Vashisth MK, Ge Y, Dai Q, He F, Wang X
Biochemical and biophysical research communications 2023 Jan 1;638:103-111
Biochemical and biophysical research communications 2023 Jan 1;638:103-111
Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism.
Wang Y, Lu Z, Huang Y, Jia W, Wang W, Zhang X, Chen C, Li Y, Yang C, Jiang G
Nanomedicine (London, England) 2023 Feb;18(3):217-231
Nanomedicine (London, England) 2023 Feb;18(3):217-231
Collagen-EGCG Combination Synergistically Prevents UVB-Induced Skin Photoaging in Nude Mice.
Fan Z, Zhou Y, Gan B, Li Y, Chen H, Peng X, Zhou Y
Macromolecular bioscience 2023 Dec;23(12):e2300251
Macromolecular bioscience 2023 Dec;23(12):e2300251
Bauhinia championii alleviates extracellular matrix degradation in IL-1β induced chondrocytes via miRNA-145-5p/TLR4/NF-κB axis.
Lin J, Huang Y, Lin X, Liu W, Wu X, Qiu H, Wang R
Heliyon 2023 Aug;9(8):e19138
Heliyon 2023 Aug;9(8):e19138
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678
Inflammation 2023 Apr;46(2):655-678
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Lu R, Wang YG, Qu Y, Wang SX, Peng C, You H, Zhu W, Chen A
Bone & joint research 2023 Apr 6;12(4):259-273
Bone & joint research 2023 Apr 6;12(4):259-273
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study.
Ding Q, Zhang R, Sheng G, Wang T, Jing S, Ma T, Wang S, Zhao H, Wu H, Li W
Journal of inflammation (London, England) 2023 Apr 13;20(1):14
Journal of inflammation (London, England) 2023 Apr 13;20(1):14
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Zhang ZF, Liu F, Zhang HR, Liu B, Zheng SQ, Ye WQ, Ding JN, Zhou ZJ, Luo HX, Wu F, Guo XM, Zhou JY, Guo YH
Discover oncology 2023 Apr 13;14(1):43
Discover oncology 2023 Apr 13;14(1):43
Interleukin-26 Expression in Inflammatory Bowel Disease and Its Immunoregulatory Effects on Macrophages.
Song D, Lai L, Lu J, Tong J, Ran Z
Frontiers in medicine 2022;9:797135
Frontiers in medicine 2022;9:797135
Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment.
Lou H, Zhang Y, Fang J, Jin Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9733742
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9733742
Network Pharmacology-Based Strategy to Investigate the Mechanisms of Cibotium barometz in Treating Osteoarthritis.
Chen GY, Wang YF, Yu XB, Liu XY, Chen JQ, Luo J, Tao QW
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1826299
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1826299
Repression of the Antioxidant Pyrroloquinoline Quinone in Skin Aging Induced by Bmi-1 Deficiency.
Li J, Liu M, Liang S, Yu Y, Gu M
BioMed research international 2022;2022:1732438
BioMed research international 2022;2022:1732438
MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension.
Chi PL, Cheng CC, Hung CC, Wang MT, Liu HY, Ke MW, Shen MC, Lin KC, Kuo SH, Hsieh PP, Wann SR, Huang WC
International journal of biological sciences 2022;18(1):331-348
International journal of biological sciences 2022;18(1):331-348
Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2.
Shen C, Xu M, Xu S, Zhang S, Lin W, Li H, Zeng S, Qiu Q, Liang L, Xiao Y, Xu H
Frontiers in pharmacology 2022;13:905376
Frontiers in pharmacology 2022;13:905376
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Hu Z, Wang Y, Gao X, Zhang Y, Liu C, Zhai Y, Chang X, Li H, Li Y, Lou J, Li C
Frontiers in pharmacology 2022;13:893307
Frontiers in pharmacology 2022;13:893307
MMP1 acts as a potential regulator of tumor progression and dedifferentiation in papillary thyroid cancer.
Zhou J, Xu M, Tan J, Zhou L, Dong F, Huang T
Frontiers in oncology 2022;12:1030590
Frontiers in oncology 2022;12:1030590
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC
Reproductive biomedicine online 2022 Sep;45(3):519-530
Reproductive biomedicine online 2022 Sep;45(3):519-530
CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF-κB pathway.
Cheng T, Wu J, Xu Y, Liu C, Zhang H, Wang M
Journal of bone and mineral metabolism 2022 Sep;40(5):819-828
Journal of bone and mineral metabolism 2022 Sep;40(5):819-828
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Belinostat (PXD101) resists UVB irradiation-induced cellular senescence and skin photoaging.
Jia HJ, Ge Y, Xia J, Shi YL, Wang XB
Biochemical and biophysical research communications 2022 Oct 30;627:122-129
Biochemical and biophysical research communications 2022 Oct 30;627:122-129
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Feng Y, Zhu G, Chen R, Shi G, Peng M, Zhou Y, Fu W, Zhou P
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Wang Y, Qu M, Liu Y, Wang H, Dong Y, Zhou X
International journal of molecular sciences 2022 Oct 14;23(20)
International journal of molecular sciences 2022 Oct 14;23(20)
Antioxidant, Anti-Inflammation and Antiaging Activities of Artocarpus altilis Methanolic Extract on Urban Particulate Matter-Induced HaCaT Keratinocytes Damage.
Yang CY, Pan CC, Tseng CH, Yen FL
Antioxidants (Basel, Switzerland) 2022 Nov 21;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 21;11(11)
The miR-145-MMP1 axis is a critical regulator for imiquimod-induced cancer stemness and chemoresistance.
Zhu S, Yang N, Niu C, Wang W, Wang X, Bai J, Qiao Y, Deng S, Guan Y, Chen J
Pharmacological research 2022 May;179:106196
Pharmacological research 2022 May;179:106196
Effects of the Leptin-Mediated MAPK/ERK Signaling Pathway on Collagen II Expression in Knee Cartilage of Newborn Male Mice from Obese Maternal Offspring.
Wang W, Zhang J, Huo Y, Zheng Y, Gui Y
Biomolecules 2022 Mar 21;12(3)
Biomolecules 2022 Mar 21;12(3)
The Effects and Mechanisms of the Rapamycin-eluting Stent in Urethral Stricture Prevention in Rabbits.
Zhang T, Zhao W, Ren T, Chen J, Chen Z, Wang Y, Cheng X, Wu J, Yuan C, He T
Balkan medical journal 2022 Mar 14;39(2):107-114
Balkan medical journal 2022 Mar 14;39(2):107-114
Identity of MMP1 and its effects on tumor progression in head and neck squamous cell carcinoma.
Zhang G, Li T, Tan G, Song Y, Liu Q, Wang K, Ai J, Zhou Z, Li W
Cancer medicine 2022 Jun;11(12):2516-2530
Cancer medicine 2022 Jun;11(12):2516-2530
Liposomes Encapsulating Morin: Investigation of Physicochemical Properties, Dermal Absorption Improvement and Anti-Aging Activity in PM-Induced Keratinocytes.
Tran HM, Yang CY, Wu TH, Yen FL
Antioxidants (Basel, Switzerland) 2022 Jun 16;11(6)
Antioxidants (Basel, Switzerland) 2022 Jun 16;11(6)
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway.
Jia N, Ma H, Zhang T, Wang L, Cui J, Zha Y, Ding Y, Wang J
International immunopharmacology 2022 Jul;108:108854
International immunopharmacology 2022 Jul;108:108854
Allergy-induced systemic inflammation impairs tendon quality.
Lehner C, Spitzer G, Langthaler P, Jakubecova D, Klein B, Weissenbacher N, Wagner A, Gehwolf R, Trinka E, Iglseder B, Paulweber B, Aigner L, Couillard-Després S, Weiss R, Tempfer H, Traweger A
EBioMedicine 2022 Jan;75:103778
EBioMedicine 2022 Jan;75:103778
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2022 Feb;43(2):417-428
Acta pharmacologica Sinica 2022 Feb;43(2):417-428
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes.
Xie Y, Sahin M, Sinha S, Wang Y, Nargund AM, Lyu Y, Han S, Dong Y, Hsieh JJ, Leslie CS, Cheng EH
Nature cancer 2022 Feb;3(2):188-202
Nature cancer 2022 Feb;3(2):188-202
Effects of intra-articular inoculation with Mycoplasma bovis on immunological responses in calf joints.
Nishi K, Hirano Y, Sato A, Eguchi A, Matsuda K, Toda M, Watanabe T, Iwasaki T, Takahashi N, Hosotani M, Watanabe R, Kato T, Ohtsuka H, Gondaira S, Higuchi H
Veterinary immunology and immunopathology 2022 Feb;244:110364
Veterinary immunology and immunopathology 2022 Feb;244:110364
S100A10 regulates tumor necrosis factor alpha-induced apoptosis in chondrocytes via the reactive oxygen species/nuclear factor-kappa B pathway.
Guo Y, Li R, Dang X
Biotechnology and applied biochemistry 2022 Dec;69(6):2284-2295
Biotechnology and applied biochemistry 2022 Dec;69(6):2284-2295
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Wang Y, Ouyang Q, Chang X, Yang M, He J, Tian Y, Sheng J
Drug delivery 2022 Dec;29(1):871-881
Drug delivery 2022 Dec;29(1):871-881
Ursolic acid alleviates Kupffer cells pyroptosis in liver fibrosis by the NOX2/NLRP3 inflammasome signaling pathway.
Wan Y, Zhang W, Huang C, Jian J, Zhang Y, Liu Q, Chen P, Zhu X
International immunopharmacology 2022 Dec;113(Pt A):109321
International immunopharmacology 2022 Dec;113(Pt A):109321
Circ_0011129 Encapsulated by the Small Extracellular Vesicles Derived from Human Stem Cells Ameliorate Skin Photoaging.
Zhang Y, Zhang M, Yao A, Xie Y, Lin J, Sharifullah F, Hong Y, Chen H, Cheng F, Lai W
International journal of molecular sciences 2022 Dec 6;23(23)
International journal of molecular sciences 2022 Dec 6;23(23)
LncRNA HIF1A-AS1 Regulates the Cellular Function of HUVECs by Globally Regulating mRNA and miRNA Expression.
Gong Z, Yang J, Dong J, Li H, Wang B, Du K, Zhang C, Chen L
Frontiers in bioscience (Landmark edition) 2022 Dec 21;27(12):330
Frontiers in bioscience (Landmark edition) 2022 Dec 21;27(12):330
Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase.
Koike H, Nishida Y, Shinomura T, Ohkawara B, Ohno K, Zhuo L, Kimata K, Ushida T, Imagama S
International journal of molecular sciences 2022 Apr 7;23(8)
International journal of molecular sciences 2022 Apr 7;23(8)
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Ma J, Hu X, Dai B, Wang Q, Wang H
PeerJ 2021;9:e11259
PeerJ 2021;9:e11259
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
Chen Y, Zhou X, Huang S, Lan Y, Yan R, Shi X, Li X, Zhang Y, Lei Z, Fan D
Frontiers in bioengineering and biotechnology 2021;9:793778
Frontiers in bioengineering and biotechnology 2021;9:793778
RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7.
Cheng J, Duan X, Fu X, Jiang Y, Yang P, Cao C, Li Q, Zhang J, Hu X, Zhang X, Ao Y
Frontiers in cell and developmental biology 2021;9:638382
Frontiers in cell and developmental biology 2021;9:638382
Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways.
Chen GY, Chen JQ, Liu XY, Xu Y, Luo J, Wang YF, Zhou TL, Yan ZR, Zhou L, Tao QW
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6634837
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6634837
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Lu R, Yu X, Liang S, Cheng P, Wang Z, He ZY, Lv ZT, Wan J, Mo H, Zhu WT, Chen AM
Frontiers in pharmacology 2021;12:761922
Frontiers in pharmacology 2021;12:761922
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Pei W, Huang X, Ni B, Zhang R, Niu G, You H
Frontiers in pharmacology 2021;12:730312
Frontiers in pharmacology 2021;12:730312
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Aihaiti Y, Song Cai Y, Tuerhong X, Ni Yang Y, Ma Y, Shi Zheng H, Xu K, Xu P
Frontiers in pharmacology 2021;12:672054
Frontiers in pharmacology 2021;12:672054
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Huang X, Pei W, Ni B, Zhang R, You H
European journal of pharmacology 2021 Sep 5;906:174232
European journal of pharmacology 2021 Sep 5;906:174232
Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes.
Teng WL, Huang PH, Wang HC, Tseng CH, Yen FL
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Oleanolic Acid Nanofibers Attenuated Particulate Matter-Induced Oxidative Stress in Keratinocytes.
Fu H, Yen FL, Huang PH, Yang CY, Yen CH
Antioxidants (Basel, Switzerland) 2021 Sep 2;10(9)
Antioxidants (Basel, Switzerland) 2021 Sep 2;10(9)
Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model.
Zhao B, Zhang X, Zhang Y, Lu Y, Zhang W, Lu S, Fu Y, Zhou Y, Zhang J, Zhang J
Stem cells and development 2021 Sep 15;30(18):922-933
Stem cells and development 2021 Sep 15;30(18):922-933
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Guan X, Yu D, HuangFu M, Huang Z, Dou T, Liu Y, Zhou L, Li X, Wang L, Liu H, Wang J, Chen X
Biochemical pharmacology 2021 Oct;192:114742
Biochemical pharmacology 2021 Oct;192:114742
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
Li Y, Zeng N, Qin Z, Chen Y, Lu Q, Cheng Y, Xia Q, Lu Z, Gu N, Luo D
Nanoscale 2021 Oct 8;13(38):16104-16112
Nanoscale 2021 Oct 8;13(38):16104-16112
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Gao XX, Liu CH, Hu ZL, Li HY, Chang X, Li YY, Zhang YY, Zhai Y, Li CQ
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Cold exposure and capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling.
Qin JC, Yu WT, Li HX, Liang YQ, Nong FF, Wen B
World journal of gastroenterology 2021 Oct 21;27(39):6615-6630
World journal of gastroenterology 2021 Oct 21;27(39):6615-6630
High fibular osteotomy ameliorates medial compartment knee osteoarthritis in a rabbit model.
Yan F, Zhao X, Duan S, Maimaiti A, Qi Y, Li M, Maimaiti M, Li W
Journal of biomechanics 2021 Nov 9;128:110734
Journal of biomechanics 2021 Nov 9;128:110734
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
Xu K, Gao Y, Yang L, Liu Y, Wang C
Connective tissue research 2021 Jul;62(4):475-484
Connective tissue research 2021 Jul;62(4):475-484
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
Shi Y, He W, Zhong M, Yu M
Genomics 2021 Jul;113(4):1988-1998
Genomics 2021 Jul;113(4):1988-1998
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Sang W, Xue S, Jiang Y, Lu H, Zhu L, Wang C, Ma J
Life sciences 2021 Aug 1;278:119528
Life sciences 2021 Aug 1;278:119528
Novel histopathological classification of meningiomas based on dural invasion.
Murase M, Tamura R, Kuranari Y, Sato M, Ohara K, Morimoto Y, Yoshida K, Toda M
Journal of clinical pathology 2021 Apr;74(4):238-243
Journal of clinical pathology 2021 Apr;74(4):238-243
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, Xiong Z, Yang S
BioMed research international 2020;2020:3126182
BioMed research international 2020;2020:3126182
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Jiang SB, Lu YS, Liu T, Li LM, Wang HX, Wu Y, Gao XH, Chen HD
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Niu X, Lin X, Chen X, Xu S, Huang Z, Tang Q
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Lu H, Chen W, Liu W, Si Y, Zhao T, Lai X, Kang Z, Sun X, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally.
Wang Y, Ding X, Liu B, Li M, Chang Y, Shen H, Xie SM, Xing L, Li Y
Molecular carcinogenesis 2020 Jan;59(1):73-86
Molecular carcinogenesis 2020 Jan;59(1):73-86
4-Hydroxy-7-oxo-5-heptenoic acid lactone is a potent inducer of brain cancer cell invasiveness that may contribute to the failure of anti-angiogenic therapies.
Tomko N, Kluever M, Wu C, Zhu J, Wang Y, Salomon RG
Free radical biology & medicine 2020 Jan;146:234-256
Free radical biology & medicine 2020 Jan;146:234-256
Intra-articular collagenase in the spinal facet joint induces pain, DRG neuron dysregulation and increased MMP-1 absent evidence of joint destruction.
Ita ME, Ghimire P, Welch RL, Troche HR, Winkelstein BA
Scientific reports 2020 Dec 15;10(1):21965
Scientific reports 2020 Dec 15;10(1):21965
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Schoenenberger AD, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, Widmer J, Maniura-Weber K, Fucentese SF, Traweger A, Silvan U, Snedeker JG
Biomaterials 2020 Aug;249:120034
Biomaterials 2020 Aug;249:120034
Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway.
Yang YF, Chang YC, Jan YH, Yang CJ, Huang MS, Hsiao M
Oncogenesis 2020 Aug 29;9(8):78
Oncogenesis 2020 Aug 29;9(8):78
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Huang X, You Y, Xi Y, Ni B, Chu X, Zhang R, You H
Inflammation 2020 Apr;43(2):619-628
Inflammation 2020 Apr;43(2):619-628
Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis.
Xi Y, Huang X, Tan G, Chu X, Zhang R, Ma X, Ni B, You H
European journal of pharmacology 2020 Apr 15;873:172925
European journal of pharmacology 2020 Apr 15;873:172925
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
You S, Liu S, Dong X, Li H, Zhu Y, Hu L
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.
Liu X, Zhou ZH, Li W, Zhang SK, Li J, Zhou MJ, Song JW
Frontiers in oncology 2019;9:216
Frontiers in oncology 2019;9:216
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Yao H, Wei S, Xiang Y, Wu Z, Liu W, Wang B, Li X, Xu H, Zhao J, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Tricetin Protects Rat Chondrocytes against IL-1β-Induced Inflammation and Apoptosis.
Sun FF, Hu PF, Xiong Y, Bao JP, Qian J, Wu LD
Oxidative medicine and cellular longevity 2019;2019:4695381
Oxidative medicine and cellular longevity 2019;2019:4695381
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Tu C, Huang X, Xiao Y, Song M, Ma Y, Yan J, You H, Wu H
Frontiers in pharmacology 2019;10:41
Frontiers in pharmacology 2019;10:41
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Chen Y, Liu H, Huang H, Ma Y, Wang R, Hu Y, Zheng X, Chen C, Tang H
Frontiers in pharmacology 2019;10:1574
Frontiers in pharmacology 2019;10:1574
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Tu C, Ma Y, Song M, Yan J, Xiao Y, Wu H
European journal of pharmacology 2019 Sep 5;858:172445
European journal of pharmacology 2019 Sep 5;858:172445
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, Ni B, Cheng H, You H
European journal of pharmacology 2019 Sep 15;859:172481
European journal of pharmacology 2019 Sep 15;859:172481
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Cecen B, Keles D, Oktay G, Kozaci LD
Chemico-biological interactions 2019 Sep 1;310:108730
Chemico-biological interactions 2019 Sep 1;310:108730
Concentration-Dependent Effects of Fibroblast-Like Synoviocytes on Collagen Gel Multiscale Biomechanics and Neuronal Signaling: Implications for Modeling Human Ligamentous Tissues.
Ita ME, Winkelstein BA
Journal of biomechanical engineering 2019 Sep 1;141(9):0910131-09101312
Journal of biomechanical engineering 2019 Sep 1;141(9):0910131-09101312
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Liang S, Wang ZG, Zhang ZZ, Chen K, Lv ZT, Wang YT, Cheng P, Sun K, Yang Q, Chen AM
Aging 2019 Oct 11;11(19):8664-8680
Aging 2019 Oct 11;11(19):8664-8680
NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway.
Huang X, Ni B, Mao Z, Xi Y, Chu X, Zhang R, Ma X, You H
Journal of cellular and molecular medicine 2019 Nov;23(11):7525-7534
Journal of cellular and molecular medicine 2019 Nov;23(11):7525-7534
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
Yu H, Zeng R, Lin Y, Li X, Tasneem S, Yang Z, Qiu YX, Li B, Wang YH, Cai X, Wang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
Wang S, Yao Y, Rao C, Zheng G, Chen W
International journal of oncology 2019 Mar;54(3):966-980
International journal of oncology 2019 Mar;54(3):966-980
MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus.
Shi C, Wu L, Lin W, Cai Y, Zhang Y, Hu B, Gao R, Im HJ, Yuan W, Ye X, van Wijnen AJ
Gene 2019 Mar 1;687:156-165
Gene 2019 Mar 1;687:156-165
Liraglutide alleviates cardiac fibrosis through inhibiting P4hα-1 expression in STZ-induced diabetic cardiomyopathy.
Zhao T, Chen H, Xu F, Wang J, Liu Y, Xing X, Guo L, Zhang M, Lu Q
Acta biochimica et biophysica Sinica 2019 Mar 1;51(3):293-300
Acta biochimica et biophysica Sinica 2019 Mar 1;51(3):293-300
Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation.
Xie X, Wang Y, Xia Y, Mao Y
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Zhang T, Li Q, Wang L, Li G
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Li X, Xue Y, Liu X, Zheng J, Shen S, Yang C, Chen J, Li Z, Liu L, Ma J, Ma T, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Isorhapontigenin Suppresses Interleukin-1β-Induced Inflammation and Cartilage Matrix Damage in Rat Chondrocytes.
Ma Y, Tu C, Liu W, Xiao Y, Wu H
Inflammation 2019 Dec;42(6):2278-2285
Inflammation 2019 Dec;42(6):2278-2285
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model.
Wang S, Ye L, Li M, Zhan H, Ye R, Li Y, Zhao Z
The Angle orthodontist 2018 Sep;88(5):624-631
The Angle orthodontist 2018 Sep;88(5):624-631
Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways.
Huang X, Pan Q, Mao Z, Wang P, Zhang R, Ma X, Chen J, You H
Molecular medicine reports 2018 Sep;18(3):2697-2704
Molecular medicine reports 2018 Sep;18(3):2697-2704
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
He XX, Shi LL, Qiu MJ, Li QT, Wang MM, Xiong ZF, Yang SL
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Huang X, Xi Y, Pan Q, Mao Z, Zhang R, Ma X, You H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation.
Wei SD, Cao D, Xu XS, Bai H, Wu H, Wang MH
Molecular medicine reports 2018 May;17(5):6909-6913
Molecular medicine reports 2018 May;17(5):6909-6913
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
Li JJ, Yin HK, Guan DX, Zhao JS, Feng YX, Deng YZ, Wang X, Li N, Wang XF, Cheng SQ, Bao Y, Xie D
British journal of cancer 2018 May;118(10):1337-1348
British journal of cancer 2018 May;118(10):1337-1348
Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes.
Huang X, Pan Q, Mao Z, Zhang R, Ma X, Xi Y, You H
Inflammation 2018 Mar;41(2):562-568
Inflammation 2018 Mar;41(2):562-568
Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis.
Rao Z, Wang S, Wang J
Molecular medicine reports 2018 Feb;17(2):3418-3424
Molecular medicine reports 2018 Feb;17(2):3418-3424
Cellular communication promotes mammosphere growth and collective invasion through microtubule‑like structures and angiogenesis.
Huang S, Yuan N, Wang G, Wu F, Feng L, Luo M, Li M, Luo A, Zhao X, Zhang L
Oncology reports 2018 Dec;40(6):3297-3312
Oncology reports 2018 Dec;40(6):3297-3312
Overexpression of matrix metalloproteinase-9 in adolescents with primary spontaneous pneumothorax for surgical intervention.
Chiu CY, Chen TP, Chen JR, Wang CJ, Yin SY, Lai SH, Wong KS
The Journal of thoracic and cardiovascular surgery 2018 Dec;156(6):2328-2336.e2
The Journal of thoracic and cardiovascular surgery 2018 Dec;156(6):2328-2336.e2
Tumor cell density regulates matrix metalloproteinases for enhanced migration.
Jayatilaka H, Umanzor FG, Shah V, Meirson T, Russo G, Starich B, Tyle P, Lee JSH, Khatau S, Gil-Henn H, Wirtz D
Oncotarget 2018 Aug 24;9(66):32556-32569
Oncotarget 2018 Aug 24;9(66):32556-32569
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Zhang HR, Lai SY, Huang LJ, Zhang ZF, Liu J, Zheng SR, Ding K, Bai X, Zhou JY
Gynecologic oncology 2018 Apr;149(1):188-197
Gynecologic oncology 2018 Apr;149(1):188-197
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Zeng L, Xiao CZ, Deng ZT, Li RH
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver.
Zheng X, Liu W, Xiang J, Liu P, Ke M, Wang B, Wu R, Lv Y
Oncotarget 2017 Nov 10;8(56):95586-95595
Oncotarget 2017 Nov 10;8(56):95586-95595
Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation.
Zhao S, Zhao Y, Guo J, Fei C, Zheng Q, Li X, Chang C
Scientific reports 2017 Mar 6;7:43849
Scientific reports 2017 Mar 6;7:43849
Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions.
Nakamura DS, Hollander JM, Uchimura T, Nielsen HC, Zeng L
BMC musculoskeletal disorders 2017 Jan 25;18(1):39
BMC musculoskeletal disorders 2017 Jan 25;18(1):39
MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN.
Chen L, Li Q, Wang J, Jin S, Zheng H, Lin J, He F, Zhang H, Ma S, Mei J, Yu J
Journal of cellular and molecular medicine 2017 Dec;21(12):3347-3359
Journal of cellular and molecular medicine 2017 Dec;21(12):3347-3359
18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Wang S, Shen Y, Qiu R, Chen Z, Chen Z, Chen W
International journal of oncology 2017 Aug;51(2):615-624
International journal of oncology 2017 Aug;51(2):615-624
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.
Li F, Fang Z, Zhang J, Li C, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li F, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H
Cell research 2016 Oct;26(10):1149-1164
Cell research 2016 Oct;26(10):1149-1164
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Zhuang K, Zhang J, Xiong M, Wang X, Luo X, Han L, Meng Y, Zhang Y, Liao W, Liu S
Cell death & disease 2016 Oct 13;7(10):e2415
Cell death & disease 2016 Oct 13;7(10):e2415
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Hong J, Liu R, Chen L, Wu B, Yu J, Gao W, Pan J, Luo X, Shi H
Thrombosis research 2016 Jan;137:148-156
Thrombosis research 2016 Jan;137:148-156
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Hu B, Shi C, Xu C, Cao P, Tian Y, Zhang Y, Deng L, Chen H, Yuan W
Scientific reports 2016 Feb 15;6:21190
Scientific reports 2016 Feb 15;6:21190
The trophoblast plug during early pregnancy: a deeper insight.
Weiss G, Sundl M, Glasner A, Huppertz B, Moser G
Histochemistry and cell biology 2016 Dec;146(6):749-756
Histochemistry and cell biology 2016 Dec;146(6):749-756
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression.
Kmiecik AM, Pula B, Suchanski J, Olbromski M, Gomulkiewicz A, Owczarek T, Kruczak A, Ambicka A, Rys J, Ugorski M, Podhorska-Okolow M, Dziegiel P
PloS one 2015;10(5):e0124865
PloS one 2015;10(5):e0124865
Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells.
Li T, Niu L, Li M, Liu Y, Xu Z, Gao X, Liu D
Molecular medicine reports 2015 Sep;12(3):3972-3978
Molecular medicine reports 2015 Sep;12(3):3972-3978
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Wu DQ, Zhong HM, Ding QH, Ba L
BMC complementary and alternative medicine 2014 Nov 15;14:444
BMC complementary and alternative medicine 2014 Nov 15;14:444
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Ding QH, Cheng Y, Chen WP, Zhong HM, Wang XH
European journal of pharmacology 2013 May 15;708(1-3):1-7
European journal of pharmacology 2013 May 15;708(1-3):1-7
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
Ding Q, Zhong H, Qi Y, Cheng Y, Li W, Yan S, Wang X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Jan;62(1):17-25
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Jan;62(1):17-25
CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2.
Zhang M, Liu Y, Feng H, Bian X, Zhao W, Yang Z, Gu B, Li Z, Liu Y
The American journal of pathology 2013 Feb;182(2):565-76
The American journal of pathology 2013 Feb;182(2):565-76
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.
Wu J, Wu G, Lv L, Ren YF, Zhang XJ, Xue YF, Li G, Lu X, Sun Z, Tang KF
Carcinogenesis 2012 Mar;33(3):519-28
Carcinogenesis 2012 Mar;33(3):519-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 10371-2-AP(MMP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MMP1 antibody 10371-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MMP1 (IP:10371-2-AP, 4ug; Detection:10371-2-AP 1:1000) with A549 cells lysate 1200ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 10371-2-AP(MMP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 10371-2-AP(MMP1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue