Antibody data

Product number
BS8360
Provider
Bioworld Technology, Inc
Product name
PMCH polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS8360
Antibody type
Polyclonal
Antigen
Recombinant full length Human PMCH.
Description
Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide derived from a 165 amino acid pro-MCH precursor. In addition to the hormone, the pro-MCH precursor contains a 144 amino acid mature MCH as well as a 12 amino acid neuropeptide glycine-glutamic acid (NGE) and a 19 amino acid neuropeptide glutamic acid-isoleucine (NEI). Mainly expressed in the hypothalamus, the melanin-concentrating hormone modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G protein-coupled receptor. MCHR mediates the effects of MCH through GÏ«i and/or GÏ«q signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, suggesting that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -