Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 20215-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20215-1-AP, RRID:AB_10697837
- Product name
- IGF1B-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IGF1B-Specific antibody (Cat. #20215-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references G protein-coupled estrogen receptor 1 deficiency impairs adult hippocampal neurogenesis in mice with schizophrenia.
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
The crosstalk between endothelial cells and vascular smooth muscle cells aggravates high phosphorus-induced arterial calcification.
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
IGF1 Knockdown Hinders Myocardial Development through Energy Metabolism Dysfunction Caused by ROS-Dependent FOXO Activation in the Chicken Heart.
Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.
Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway.
Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes.
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells.
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
miR-129 controls axonal regeneration via regulating insulin-like growth factor-1 in peripheral nerve injury.
Zhang C, Niu JG, Kong XR, Mi XJ, Liu Q, Chen FF, Rong WF, Liu J
Journal of chemical neuroanatomy 2023 Oct;132:102319
Journal of chemical neuroanatomy 2023 Oct;132:102319
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Zhang B, Li H, Wang Y, Li Y, Zhou Z, Hou X, Zhang X, Liu T
Ecotoxicology and environmental safety 2023 Feb;251:114557
Ecotoxicology and environmental safety 2023 Feb;251:114557
The crosstalk between endothelial cells and vascular smooth muscle cells aggravates high phosphorus-induced arterial calcification.
Lin X, Shan SK, Xu F, Zhong JY, Wu F, Duan JY, Guo B, Li FX, Wang Y, Zheng MH, Xu QS, Lei LM, Ou-Yang WL, Wu YY, Tang KX, Ullah MHE, Liao XB, Yuan LQ
Cell death & disease 2022 Jul 26;13(7):650
Cell death & disease 2022 Jul 26;13(7):650
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Raber J, Perez R, Torres ERS, Krenik D, Boutros S, Patel E, Chlebowski AC, Torres ER, Perveen Z, Penn A, Paulsen DB, Bartlett MG, Jia E, Holden S, Hall R, Morré J, Wong C, Ho E, Choi J, Stevens JF, Noël A, Bobe G, Kisby G
Environmental health perspectives 2021 May;129(5):57009
Environmental health perspectives 2021 May;129(5):57009
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Zhang K, Yang R, Chen J, Qi E, Zhou S, Wang Y, Fu Q, Chen R, Fang X
Frontiers in bioengineering and biotechnology 2020;8:428
Frontiers in bioengineering and biotechnology 2020;8:428
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
IGF1 Knockdown Hinders Myocardial Development through Energy Metabolism Dysfunction Caused by ROS-Dependent FOXO Activation in the Chicken Heart.
Gong Y, Yang J, Liu Q, Cai J, Zheng Y, Zhang Y, Yu D, Liu H, Zhang Z
Oxidative medicine and cellular longevity 2019;2019:7838754
Oxidative medicine and cellular longevity 2019;2019:7838754
Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.
Wang Y, Wu JZ, Li Y, Qi X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2089586
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2089586
Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway.
Pei X, Xiao J, Wei G, Zhang Y, Lin F, Xiong Z, Lu L, Wang X, Pang G, Jiang Y, Jiang L
Chemico-biological interactions 2019 Jan 25;298:112-120
Chemico-biological interactions 2019 Jan 25;298:112-120
Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes.
Xiao Y, Zeng M, Yin L, Li N, Xiao F
Toxicology research 2019 Jan 1;8(1):15-24
Toxicology research 2019 Jan 1;8(1):15-24
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells.
DeVore SB, Young CH, Li G, Sundararajan A, Ramaraj T, Mudge J, Schilkey F, Muth A, Thompson PR, Cherrington BD
Molecular and cellular biology 2018 Oct 1;38(19)
Molecular and cellular biology 2018 Oct 1;38(19)
Systemic administration of scAAV9-IGF1 extends survival in SOD1(G93A) ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, Li Z, Liu Y, Li C
Brain research bulletin 2018 May;139:203-210
Brain research bulletin 2018 May;139:203-210
miR-129 controls axonal regeneration via regulating insulin-like growth factor-1 in peripheral nerve injury.
Zhu H, Xue C, Yao M, Wang H, Zhang P, Qian T, Zhou S, Li S, Yu B, Wang Y, Gu X
Cell death & disease 2018 Jun 18;9(7):720
Cell death & disease 2018 Jun 18;9(7):720
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 20215-1-AP(IGF1B-Specific antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 20215-1-AP(IGF1B-Specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IGF1B-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human IGF1B-Specific. This antibody recognizes human, mouse, rat antigen. The IGF1B-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.