Antibody data
- Antibody Data
 - Antigen structure
 - References [4]
 - Comments [0]
 - Validations
 - Immunohistochemistry [1]
 
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- Product number
 - PAB16614 - Provider product page

 - Provider
 - Abnova Corporation
 - Proper citation
 - Abnova Corporation Cat#PAB16614, RRID:AB_10673720
 - Product name
 - IGF1 polyclonal antibody
 - Antibody type
 - Polyclonal
 - Description
 - Rabbit polyclonal antibody raised against recombinant IGF1.
 - Isotype
 - IgG
 - Storage
 - Store at -20°C.Aliquot to avoid repeated freezing and thawing.
 
Submitted references		Hypoactivity affects IGF-1 level and PI3K/AKT signaling pathway in cerebral structures implied in motor control.
				
A significant decline in IGF-I may predispose young Africans to subsequent cardiometabolic vulnerability.
				
IGF-I lucidity ... the murky waters begin to clear?
				
Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling.
				
		
	
			Mysoet J, Canu MH, Cieniewski-Bernard C, Bastide B, Dupont E
PloS one 2014;9(9):e107631
		PloS one 2014;9(9):e107631
A significant decline in IGF-I may predispose young Africans to subsequent cardiometabolic vulnerability.
			Schutte AE, Huisman HW, van Rooyen JM, Malan L, Malan NT, Fourie CM, Louw R, van der Westhuizen FH, Schutte R
The Journal of clinical endocrinology and metabolism 2010 May;95(5):2503-7
		The Journal of clinical endocrinology and metabolism 2010 May;95(5):2503-7
IGF-I lucidity ... the murky waters begin to clear?
			Spangenburg EE
Journal of applied physiology (Bethesda, Md. : 1985) 2010 May;108(5):1032-3
		Journal of applied physiology (Bethesda, Md. : 1985) 2010 May;108(5):1032-3
Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling.
			Sunters A, Armstrong VJ, Zaman G, Kypta RM, Kawano Y, Lanyon LE, Price JS
The Journal of biological chemistry 2010 Mar 19;285(12):8743-58
		The Journal of biological chemistry 2010 Mar 19;285(12):8743-58
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					Supportive validation
					
									
				
		- Submitted by
 - Abnova Corporation (provider)
 - Main image
 
- Experimental details
 - Immunohistochemical analysis of IGFI expression in NZ rabbit knee joint tissue. IGF1 polyclonal antibody (Cat ID # PAB16614) was used as primary antibody, dilution 1 : 200.
 - Validation comment
 - Immunohistochemistry