RA0315

antibody from Oursmab

Targeting: IGF1 IGF, IGF-I, IGF1A, IGFI

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0315

Provider

Oursmab

Product name

Xentuzumab (Biosimilar Reference Antibody) (IGF1 and IGF2)

Antibody type

Monoclonal

Description

Xentuzumab (BI 836845) is an investigational humanized monoclonal antibody that targets and neutralizes insulin-like growth factor 1 (IGF-1) and insulin-like growth factor 2 (IGF-2). It is being developed for the treatment of advanced solid tumors, particularly in combination with other therapies, aiming to inhibit the IGF signaling pathway which is often dysregulated in cancer and promotes tumor growth and survival.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Xentuzumab (Biosimilar Reference Antibody) (IGF1 and IGF2)-RA0315-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Xentuzumab (Biosimilar Reference Antibody) (IGF1 and IGF2)-RA0315 in a linear range of 15.63¨C125 ng/mL.