ABIN394774
antibody from antibodies-online
Targeting: AKR1B10
AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [4]
- ELISA [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN394774 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-144) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 76-144
- Isotype
- IgG
- Antibody clone number
- 1A6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
[Downregulation of AKR1B10 gene expression in colorectal cancer].
Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Novel role for aldose reductase in mediating acute inflammatory responses in the lung.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
[Downregulation of AKR1B10 gene expression in colorectal cancer].
Kropotova ES, Tychko RA, Zinov'eva OL, Zyrianova AF, Khankin SL, Cherkes VL, Aliev VA, Beresten' SF, Oparina NIu, Mashkova TD
Molekuliarnaia biologiia 2010 Mar-Apr;44(2):243-50
Molekuliarnaia biologiia 2010 Mar-Apr;44(2):243-50
Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours.
Heringlake S, Hofdmann M, Fiebeler A, Manns MP, Schmiegel W, Tannapfel A
Journal of hepatology 2010 Feb;52(2):220-7
Journal of hepatology 2010 Feb;52(2):220-7
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators., NORDIL investigators., BRIGHT Consortium.
American journal of human genetics 2009 Nov;85(5):628-42
American journal of human genetics 2009 Nov;85(5):628-42
Novel role for aldose reductase in mediating acute inflammatory responses in the lung.
Ravindranath TM, Mong PY, Ananthakrishnan R, Li Q, Quadri N, Schmidt AM, Ramasamy R, Wang Q
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):8128-37
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):8128-37
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Supportive validation
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- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC