orb2634961

antibody from Biorbyt

Targeting: NFIA KIAA1439, NFI-L

Western blot

Immunocytochemistry

Immunohistochemistry

Flow cytometry

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Validation data

Product number: orb2634961 - Provider product page
Provider: Biorbyt
Product name: NFIA Antibody / Nuclear Factor 1 A
Antibody type: Monoclonal
Description: Nuclear factor (NF) proteins are a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, -globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antibody clone number: PCRP-NFIA-2C6
Vial size: 100 ug
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

NFIA protein structure - orb2634961 shown in red.