HPA008884

antibody from Atlas Antibodies

Targeting: NFIA KIAA1439, NFI-L

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA008884

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA008884, RRID:AB_1854421

Product name

Anti-NFIA

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human NFIA, Gene description: nuclear factor I/A, Alternative Gene Names: KIAA1439, NFI-L, Validated applications: ICC, IHC, Uniprot ID: Q12857, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells

Qin K, Huang P, Feng R, Keller C, Peslak S, Khandros E, Saari M, Lan X, Mayuranathan T, Doerfler P, Abdulmalik O, Giardine B, Chou S, Shi J, Hardison R, Weiss M, Blobel G
Nature Genetics 2022;54(6):874-884

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CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.

Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M
Nature neuroscience 2022 Nov;25(11):1528-1542

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Transcription factor competition at the γ-globin promoters controls hemoglobin switching

Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu J, Sakon P, Pinello L, Yuan G, Bauer D, Orkin S
Nature Genetics 2021;53(4):511-520

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Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes

Hickey S, Berto S, Konopka G
Cell Reports 2019;27(6):1699-1711.e9

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YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.

Pajtler KW, Wei Y, Okonechnikov K, Silva PBG, Vouri M, Zhang L, Brabetz S, Sieber L, Gulley M, Mauermann M, Wedig T, Mack N, Imamura Kawasawa Y, Sharma T, Zuckermann M, Andreiuolo F, Holland E, Maass K, Körkel-Qu H, Liu HK, Sahm F, Capper D, Bunt J, Richards LJ, Jones DTW, Korshunov A, Chavez L, Lichter P, Hoshino M, Pfister SM, Kool M, Li W, Kawauchi D
Nature communications 2019 Sep 2;10(1):3914

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Combined allelic dosage of Nfia and Nfib regulates cortical development

Bunt J, Osinski J, Lim J, Vidovic D, Ye Y, Zalucki O, O’Connor T, Harris L, Gronostajski R, Richards L, Piper M
Brain and Neuroscience Advances 2017;1

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PAX6 does not regulate Nfia and Nfib expression during neocortical development

Bunt J, Lim J, Zhao L, Mason S, Richards L
Scientific Reports 2015;5(1)

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

Sample type

Human