Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS1584 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1584, RRID:AB_1663406
- Product name
- PKD2 (A872) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 840-890 of Human PKD2.
- Description
- PKD2 (protein kinase D2), also known as PRKD2 or HSPC187, is a widely expressed protein belonging to the protein kinase D (PKD) family of serine/threonine kinases. In mammals, there are three members of the PKD family, namely PKC Ã×, PKD2 and PKC n, and each contain a homologous catalytic domain but differ in their tissue expression and subcellular localization. PKD family members are activated by G-protein-coupled receptors (GPCRs) and are known to participate in biological processes such as proliferation, apoptosis, migration, signal transduction and vesicle shedding. Shuttling between the nucleus and the cytoplasm, PKD2 contains one PH domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers, and functions as a calcium-independent, phospholipid-dependent protein kinase.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PKD2 (A872) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate