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- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 12102-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12102-1-AP, RRID:AB_2160484
- Product name
- PBXIP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PBXIP1 antibody (Cat. #12102-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
INPP4B promotes colorectal cancer cell proliferation by activating mTORC1 signaling and cap-dependent translation.
Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.
The interplay between HPIP and casein kinase 1α promotes renal cell carcinoma growth and metastasis via activation of mTOR pathway.
HPIP promotes gastric cancer cell proliferation through activation of cap-dependent translation.
HPIP promotes thyroid cancer cell growth, migration and EMT through activating PI3K/AKT signaling pathway.
Hematopoietic pre-B cell leukemia transcription factor interacting protein is overexpressed in gastric cancer and promotes gastric cancer cell proliferation, migration, and invasion.
HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.
MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.
HPIP is upregulated in liver cancer and promotes hepatoma cell proliferation via activation of G2/M transition.
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
INPP4B promotes colorectal cancer cell proliferation by activating mTORC1 signaling and cap-dependent translation.
Ruan XH, Liu XM, Yang ZX, Zhang SP, Li QZ, Lin CS
OncoTargets and therapy 2019;12:3109-3117
OncoTargets and therapy 2019;12:3109-3117
Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.
Ji Q, Xu X, Kang L, Xu Y, Xiao J, Goodman SB, Zhu X, Li W, Liu J, Gao X, Yan Z, Zheng Y, Wang Z, Maloney WJ, Ye Q, Wang Y
Nature communications 2019 Jan 18;10(1):313
Nature communications 2019 Jan 18;10(1):313
The interplay between HPIP and casein kinase 1α promotes renal cell carcinoma growth and metastasis via activation of mTOR pathway.
Mai H, Xu X, Mei G, Hong T, Huang J, Wang T, Yan Z, Li Y, Liang Y, Li L, Jin S, You W, Ma Y, Chen L, Ye Q
Oncogenesis 2016 Oct 3;5(10):e260
Oncogenesis 2016 Oct 3;5(10):e260
HPIP promotes gastric cancer cell proliferation through activation of cap-dependent translation.
Chen B, Zhao J, Zhang S, Zhang Y, Huang Z
Oncology reports 2016 Dec;36(6):3664-3672
Oncology reports 2016 Dec;36(6):3664-3672
HPIP promotes thyroid cancer cell growth, migration and EMT through activating PI3K/AKT signaling pathway.
Wang SC, Chai DS, Chen CB, Wang ZY, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Oct;75:33-9
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Oct;75:33-9
Hematopoietic pre-B cell leukemia transcription factor interacting protein is overexpressed in gastric cancer and promotes gastric cancer cell proliferation, migration, and invasion.
Feng Y, Li L, Zhang X, Zhang Y, Liang Y, Lv J, Fan Z, Guo J, Hong T, Ji B, Ji Q, Mei G, Ding L, Zhang S, Xu X, Ye Q
Cancer science 2015 Oct;106(10):1313-22
Cancer science 2015 Oct;106(10):1313-22
HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.
Feng Y, Xu X, Zhang Y, Ding J, Wang Y, Zhang X, Wu Z, Kang L, Liang Y, Zhou L, Song S, Zhao K, Ye Q
Scientific reports 2015 Mar 24;5:9429
Scientific reports 2015 Mar 24;5:9429
MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.
Shostak K, Patrascu F, Göktuna SI, Close P, Borgs L, Nguyen L, Olivier F, Rammal A, Brinkhaus H, Bentires-Alj M, Marine JC, Chariot A
Cell death and differentiation 2014 May;21(5):811-24
Cell death and differentiation 2014 May;21(5):811-24
HPIP is upregulated in liver cancer and promotes hepatoma cell proliferation via activation of G2/M transition.
Xu X, Jiang C, Wang S, Tai Y, Wang T, Kang L, Fan Z, Li S, Li L, Fu J, Liu J, Ji Q, Wang X, Wei L, Ye Q
IUBMB life 2013 Oct;65(10):873-82
IUBMB life 2013 Oct;65(10):873-82
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Xu X, Fan Z, Kang L, Han J, Jiang C, Zheng X, Zhu Z, Jiao H, Lin J, Jiang K, Ding L, Zhang H, Cheng L, Fu H, Song Y, Jiang Y, Liu J, Wang R, Du N, Ye Q
The Journal of clinical investigation 2013 Feb;123(2):630-45
The Journal of clinical investigation 2013 Feb;123(2):630-45
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12102-1-AP(PBXIP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PBXIP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PBXIP1. This antibody recognizes human antigen. The PBXIP1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 12102-1-AP(PBXIP1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
