RA0689

antibody from Oursmab

Targeting: SLC1A5 AAAT, ASCT2, M7V1, RDRC

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0689

Provider

Oursmab

Product name

Idactamab (Biosimilar Reference Antibody) (SLC1A5)

Antibody type

Monoclonal

Description

Idactamab is an investigational, immunoglobulin G1 kappa (IgG1-¦Ê) monoclonal antibody being developed for the treatment of hematological malignancies. It functions as a targeted inhibitor of the amino acid transporter SLC1A5, also known as ASCT2 (Alanine, Serine, Cysteine Transporter 2). By binding with high affinity to SLC1A5/ASCT2 on the surface of cancer cells, idactamab blocks its transporter activity. This inhibition deprives malignant cells of critical nutrients, particularly glutamine, which is essential for their rapid proliferation, energy production (through anaplerosis of the TCA cycle), and biosynthesis of proteins and nucleotides.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.