PSMC3

gene product
TBP-1, TBP1
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]
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312 antibodies from 32 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
9 antibodies
OriGene
27 antibodies
GeneTex
15 antibodies
NovoPro Bioscience Inc.
5 antibodies
antibodies-online
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Invitrogen Antibodies
6 antibodies
Biorbyt
13 antibodies
Enzo Life Sciences
6 antibodies
LifeSpan BioSciences, Inc.
59 antibodies
Aviva Systems Biology
6 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
2 antibodies
Proteintech Group
1 antibody
Signalway Antibody LLC
1 antibody
Bethyl Laboratories
2 antibodies
St John's Laboratory
3 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
5 antibodies
Acris Antibodies GmbH
1 antibody
Abgent
3 antibodies
RabMAbs
3 antibodies
Creative Diagnostics
8 antibodies
Creative Biolabs
5 antibodies
MyBioSource
6 antibodies
United States Biological
43 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
ProSci
1 antibody
Sigma-Aldrich
5 antibodies
Abbiotec
1 antibody
Abbexa
3 antibodies