Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10229-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10229-1-AP, RRID:AB_2182917
- Product name
- SAE1 antibody
- Antibody type
- Polyclonal
- Description
- SAE1 antibody (Cat. #10229-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.
Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation.
Mild microwave hyperthermia promotes mitotic catastrophe, induces time-delayed cGAS-STING activation and restores sensitivity to anti-PDL1 therapy in Pan02 pancreatic cancer model.
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis.
Wusiman R, Haimiti S, Abuduaini H, Yang M, Wang Y, Gu M, Sailike A, Gao L
Biochemical pharmacology 2025 Jul;237:116920
Biochemical pharmacology 2025 Jul;237:116920
Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation.
Loison L, Huré M, Lefranc B, Leprince J, Bôle-Feysot C, Coëffier M, Ribet D
Gut microbes 2025 Dec;17(1):2446392
Gut microbes 2025 Dec;17(1):2446392
Mild microwave hyperthermia promotes mitotic catastrophe, induces time-delayed cGAS-STING activation and restores sensitivity to anti-PDL1 therapy in Pan02 pancreatic cancer model.
Li N, He J, Chen M, Liang S, Zhang C, Pan W, Wang Q, Piao F, Wang R, Yu J, Gong G
Oncoimmunology 2025 Dec 31;14(1):2602216
Oncoimmunology 2025 Dec 31;14(1):2602216
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Wu YJ, Huang ST, Chang YH, Lin SY, Lin WL, Chen YJ, Chien ST
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
Liu Y, Wang X, Zeng X, Wu Y, Liu X, Tan J, Li X
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J, Xu D
Nature communications 2022 Nov 22;13(1):7153
Nature communications 2022 Nov 22;13(1):7153
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
Ma X, Yang T, Luo Y, Wu L, Jiang Y, Song Z, Pan T, Liu B, Liu G, Liu J, Yu F, He Z, Zhang W, Yang J, Liang L, Guan Y, Zhang X, Li L, Cai W, Tang X, Gao S, Deng K, Zhang H
eLife 2019 Jan 17;8
eLife 2019 Jan 17;8
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis.
Chen D, Zheng W, Lin A, Uyhazi K, Zhao H, Lin H
Current biology : CB 2012 Mar 6;22(5):420-5
Current biology : CB 2012 Mar 6;22(5):420-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SAE1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SAE1. This antibody recognizes human,mouse,rat antigen. The SAE1 antibody has been validated for the following applications: ELISA, WB analysis.