Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 14286-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14286-1-AP, RRID:AB_2279646
- Product name
- HLTF antibody
- Antibody type
- Polyclonal
- Description
- HLTF antibody (Cat. #14286-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CD137L promotes immune surveillance in melanoma via HLTF regulation.
DNA2 enables growth by restricting recombination-restarted replication.
LINC01088 prevents ferroptosis in glioblastoma by enhancing SLC7A11 via HLTF/USP7 axis.
CBX3 Downregulates HLTF to Activate PI3K/AKT Signaling Promoting Cholangiocarcinoma.
Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancers.
Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancers.
A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation.
HLTF promotes hepatocellular carcinoma progression by enhancing SRSF1 stability and activating ERK/MAPK pathway.
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response.
Break-induced replication promotes fragile telomere formation.
HLTF suppresses the migration and invasion of colorectal cancer cells via TGF‑β/SMAD signaling in vitro.
Liang L, Zhu L, Li X, Zhou W, Zhang Y, Hung MC, Zhang G, Chen Y, Kuang X, Su J, Liu J, Chen X, Liu H
Nature communications 2025 Sep 26;16(1):8478
Nature communications 2025 Sep 26;16(1):8478
DNA2 enables growth by restricting recombination-restarted replication.
Hudson JJR, Appanah R, Jones D, Davidson K, Budden AM, Vaitsiankova A, Chan KL, Caldecott KW, Carr AM, Rass U
Nature 2025 Oct;646(8086):992-1000
Nature 2025 Oct;646(8086):992-1000
LINC01088 prevents ferroptosis in glioblastoma by enhancing SLC7A11 via HLTF/USP7 axis.
Zhou Y, Zhao Z, Jiang C, Nie C, Xiao D, Wu Z, Yu H, Zheng J, Wang X, Jiang X
Clinical and translational medicine 2025 Mar;15(3):e70257
Clinical and translational medicine 2025 Mar;15(3):e70257
CBX3 Downregulates HLTF to Activate PI3K/AKT Signaling Promoting Cholangiocarcinoma.
Xie M, Liang H, Mao Y, Yao Y, Tian B
Advanced biology 2025 Jan;9(1):e2400413
Advanced biology 2025 Jan;9(1):e2400413
Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancers.
Lee J, Sohn EJ, Lee J, Cheng AY, Taglialatela A, Ciccia A, Min J
Nucleic acids research 2025 Aug 11;53(15)
Nucleic acids research 2025 Aug 11;53(15)
Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancers.
Lee J, Sohn EJ, Lee J, Taglialatela A, Ciccia A, Min J
bioRxiv : the preprint server for biology 2025 Apr 19;
bioRxiv : the preprint server for biology 2025 Apr 19;
A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation.
Ubieto-Capella P, Ximénez-Embún P, Giménez-Llorente D, Losada A, Muñoz J, Méndez J
Cell reports 2024 Apr 23;43(4):114024
Cell reports 2024 Apr 23;43(4):114024
HLTF promotes hepatocellular carcinoma progression by enhancing SRSF1 stability and activating ERK/MAPK pathway.
Xu Y, Ke S, Lu S, Wang C, Li Z, Feng Z, Yu H, Bai M, Qian B, Yin B, Li X, Hua Y, Jiang H, Ma Y
Oncogenesis 2023 Jan 20;12(1):2
Oncogenesis 2023 Jan 20;12(1):2
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Gao W, Rui Y, Li G, Zhai C, Su J, Liu H, Zheng W, Zheng B, Zhang W, Yang Y, Hua S, Yu X
Frontiers in immunology 2021;12:740713
Frontiers in immunology 2021;12:740713
Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response.
McMahon KA, Stroud DA, Gambin Y, Tillu V, Bastiani M, Sierecki E, Polinkovsky ME, Hall TE, Gomez GA, Wu Y, Parat MO, Martel N, Lo HP, Khanna KK, Alexandrov K, Daly R, Yap A, Ryan MT, Parton RG
eLife 2021 Jun 18;10
eLife 2021 Jun 18;10
Break-induced replication promotes fragile telomere formation.
Yang Z, Takai KK, Lovejoy CA, de Lange T
Genes & development 2020 Oct 1;34(19-20):1392-1405
Genes & development 2020 Oct 1;34(19-20):1392-1405
HLTF suppresses the migration and invasion of colorectal cancer cells via TGF‑β/SMAD signaling in vitro.
Liu L, Liu H, Zhou Y, He J, Liu Q, Wang J, Zeng M, Yuan D, Tan F, Zhou Y, Pei H, Zhu H
International journal of oncology 2018 Dec;53(6):2780-2788
International journal of oncology 2018 Dec;53(6):2780-2788
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HLTF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HLTF. This antibody recognizes human, mouse, rat antigen. The HLTF antibody has been validated for the following applications: ELISA, WB analysis.
