10827-1-AP
antibody from Proteintech Group
Targeting: KAT5
cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5
Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 10827-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10827-1-AP, RRID:AB_2128431
- Product name
- KAT5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KAT5 antibody (Cat. #10827-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Securin acetylation prevents precocious separase activation and premature sister chromatid separation.
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin.
BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin.
A NPAS4-NuA4 complex couples synaptic activity to DNA repair.
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis.
Acetylated DNMT1 Downregulation and Related Regulatory Factors Influence Metastatic Melanoma Patients Survival.
DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation.
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
Impaired FGF10 Signaling and Epithelial Development in Experimental Lung Hypoplasia With Esophageal Atresia.
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
The transcriptional coactivator TAZ regulates reciprocal differentiation of T(H)17 cells and T(reg) cells.
Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.
MDR1 mediated chemoresistance: BMI1 and TIP60 in action.
Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm).
ANP32E is a histone chaperone that removes H2A.Z from chromatin.
Wang T, Zou Y, Meng H, Zheng P, Teng J, Huang N, Chen J
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin.
Wang Z, Yang X, Chen D, Liu Y, Li Z, Duan S, Zhang Z, Jiang X, Stockwell BR, Gu W
Nature communications 2024 Mar 21;15(1):2531
Nature communications 2024 Mar 21;15(1):2531
BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.
Liu W, Wang S, Lin L, Zou R, Sun H, Zeng K, Wu Y, Li Y, Shigeaki K, Wang X, Wang C, Zhao Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166974
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166974
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Wu YQ, Zhang CS, Xiong J, Cai DQ, Wang CZ, Wang Y, Liu YH, Wang Y, Li Y, Wu J, Wu J, Lan B, Wang X, Chen S, Cao X, Wei X, Hu HH, Guo H, Yu Y, Ghafoor A, Xie C, Wu Y, Xu Z, Zhang C, Zhu M, Huang X, Sun X, Lin SY, Piao HL, Zhou J, Lin SC
Cell research 2023 Nov;33(11):835-850
Cell research 2023 Nov;33(11):835-850
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, Zhang L, Qian Y, Sun Y, Wang A, Zou Y, Chen W, Li Y, Huang L, Yang Y, Zhao Y, Cheng X
Science advances 2023 Jun 2;9(22):eadg4993
Science advances 2023 Jun 2;9(22):eadg4993
Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Liu N, Konuma T, Sharma R, Wang D, Zhao N, Cao L, Ju Y, Liu D, Wang S, Bosch A, Sun Y, Zhang S, Ji D, Nagatoishi S, Suzuki N, Kikuchi M, Wakamori M, Zhao C, Ren C, Zhou TJ, Xu Y, Meslamani J, Fu S, Umehara T, Tsumoto K, Akashi S, Zeng L, Roeder RG, Walsh MJ, Zhang Q, Zhou MM
Molecular cell 2023 Jul 6;83(13):2206-2221.e11
Molecular cell 2023 Jul 6;83(13):2206-2221.e11
Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin.
Zhu Y, Hart GW
Cell 2023 Jan 19;186(2):428-445.e27
Cell 2023 Jan 19;186(2):428-445.e27
A NPAS4-NuA4 complex couples synaptic activity to DNA repair.
Pollina EA, Gilliam DT, Landau AT, Lin C, Pajarillo N, Davis CP, Harmin DA, Yap EL, Vogel IR, Griffith EC, Nagy MA, Ling E, Duffy EE, Sabatini BL, Weitz CJ, Greenberg ME
Nature 2023 Feb;614(7949):732-741
Nature 2023 Feb;614(7949):732-741
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Zhang X, Li T, Yang M, Du Q, Wang R, Fu B, Tan Y, Cao M, Chen Y, Wang Q, Hu R
Cell death & disease 2022 Feb 10;13(2):138
Cell death & disease 2022 Feb 10;13(2):138
Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis.
Akbar H, Cao J, Wang D, Yuan X, Zhang M, Muthusamy S, Song X, Liu X, Aikhionbare F, Yao X, Gao X, Liu X
Journal of molecular cell biology 2022 Dec 26;14(8)
Journal of molecular cell biology 2022 Dec 26;14(8)
Acetylated DNMT1 Downregulation and Related Regulatory Factors Influence Metastatic Melanoma Patients Survival.
Zhang X, Bustos MA, Shoji Y, Ramos RI, Iida Y, Gentry R, Takeshima TL, Hoon DSB
Cancers 2021 Sep 18;13(18)
Cancers 2021 Sep 18;13(18)
DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation.
Hishikawa A, Hayashi K, Kubo A, Miyashita K, Hashiguchi A, Kinouchi K, Yoshimoto N, Nakamichi R, Akashio R, Sugita E, Azegami T, Monkawa T, Suematsu M, Itoh H
iScience 2021 Dec 17;24(12):103436
iScience 2021 Dec 17;24(12):103436
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
You Z, Jiang WX, Qin LY, Gong Z, Wan W, Li J, Wang Y, Zhang H, Peng C, Zhou T, Tang C, Liu W
Nature communications 2019 Dec 19;10(1):5792
Nature communications 2019 Dec 19;10(1):5792
Impaired FGF10 Signaling and Epithelial Development in Experimental Lung Hypoplasia With Esophageal Atresia.
Wang J, Liu H, Gao L, Liu X
Frontiers in pediatrics 2018;6:109
Frontiers in pediatrics 2018;6:109
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Zhang Y, Ji G, Han S, Shao Z, Lu Z, Huo L, Zhang J, Yang R, Feng Q, Shen H, Wang H, Li X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
The transcriptional coactivator TAZ regulates reciprocal differentiation of T(H)17 cells and T(reg) cells.
Geng J, Yu S, Zhao H, Sun X, Li X, Wang P, Xiong X, Hong L, Xie C, Gao J, Shi Y, Peng J, Johnson RL, Xiao N, Lu L, Han J, Zhou D, Chen L
Nature immunology 2017 Jul;18(7):800-812
Nature immunology 2017 Jul;18(7):800-812
Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.
Barral S, Morozumi Y, Tanaka H, Montellier E, Govin J, de Dieuleveult M, Charbonnier G, Couté Y, Puthier D, Buchou T, Boussouar F, Urahama T, Fenaille F, Curtet S, Héry P, Fernandez-Nunez N, Shiota H, Gérard M, Rousseaux S, Kurumizaka H, Khochbin S
Molecular cell 2017 Apr 6;66(1):89-101.e8
Molecular cell 2017 Apr 6;66(1):89-101.e8
MDR1 mediated chemoresistance: BMI1 and TIP60 in action.
Banerjee Mustafi S, Chakraborty PK, Naz S, Dwivedi SK, Street M, Basak R, Yang D, Ding K, Mukherjee P, Bhattacharya R
Biochimica et biophysica acta 2016 Aug;1859(8):983-93
Biochimica et biophysica acta 2016 Aug;1859(8):983-93
Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm).
Yu H, Diao H, Wang C, Lin Y, Yu F, Lu H, Xu W, Li Z, Shi H, Zhao S, Zhou Y, Zhang Y
Molecular & cellular proteomics : MCP 2015 Apr;14(4):1009-23
Molecular & cellular proteomics : MCP 2015 Apr;14(4):1009-23
ANP32E is a histone chaperone that removes H2A.Z from chromatin.
Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A
Nature 2014 Jan 30;505(7485):648-53
Nature 2014 Jan 30;505(7485):648-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 10827-1-AP(KAT5 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KAT5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KAT5. This antibody recognizes human,mouse,rat antigen. The KAT5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.