CABT-36063RH

antibody from Creative Diagnostics

Targeting: NPM1 B23, NPM

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-36063RH

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#CABT-36063RH, RRID:AB_2356998

Product name

Rabbit Anti-Human NPM1 monoclonal antibody, clone TQ347

Antibody type

Monoclonal

Description

Nucleophosmin (NPM) is a nucleolar protein for regulating ribosome biosynthesis and centrosome duplication. The NPM gene is frequently rearranged in various types of lymphomas such as anaplastic lymphoma kinase (ALK) . A C-terminal mutation occurs in acute myelogenous leukemia (AML) and prevents localization to the nucleolus, resulting in cytoplasmic distribution. NPM is frequently overexpressed in diverse solid tumors such as carcinoma of the lung and breast, colon, prostate, stomach, lymphoid and myeloid tumors.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TQ347

Storage

2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.