PAB12536

antibody from Abnova Corporation

Targeting: NPM1 B23, NPM

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

PAB12536

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12536, RRID:AB_10553724

Product name

NPM1, mutant nucleophosmin polyclonal antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to amino acids 250-298 of human NPM1.

Description

Rabbit polyclonal antibody raised against synthetic peptide of NPM1.

Reactivity

Human

Host

Rabbit

Vial size

100 μL

Storage

Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.

El Hajj H, Dassouki Z, Berthier C, Raffoux E, Ades L, Legrand O, Hleihel R, Sahin U, Tawil N, Salameh A, Zibara K, Darwiche N, Mohty M, Dombret H, Fenaux P, de Thé H, Bazarbachi A
Blood 2015 May 28;125(22):3447-54

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Nucleophosmin and cancer.

Grisendi S, Mecucci C, Falini B, Pandolfi PP
Nature reviews. Cancer 2006 Jul;6(7):493-505

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Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.

Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, La Starza R, Diverio D, Colombo E, Santucci A, Bigerna B, Pacini R, Pucciarini A, Liso A, Vignetti M, Fazi P, Meani N, Pettirossi V, Saglio G, Mandelli F, Lo-Coco F, Pelicci PG, Martelli MF, GIMEMA Acute Leukemia Working Party
The New England journal of medicine 2005 Jan 20;352(3):254-66