Antibody data

Product number
11-4033-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Nucleophosmin Antibody
Antibody type
Polyclonal
Description
Nucleophosmin (NPM1) is a multifunctional, ubiquitously expressed nucleolar phoshoprotein which shuttles continuously between the nucleus and cytoplasm and plays an important role in cell proliferation and apoptosis. This protein exerts its functions through the interaction with a multiplicity of biological partners, specifically recognizes DNA G-quadruplexes through its C-terminal region. It is mainly localized in the nucleolus and has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. Mutations at exon 12 of NPM1 gene is a hallmark of cytogenetically normal acute myeloid leukemia.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Nucleo
phosmin protein (amino acids 18-236
) was used as the immunogen for thi
s antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
NPM1 protein structure - 11-4033-25 shown in red.