PA1931

antibody from Boster Biological Technology
Targeting: NPM1 B23, NPM
Provider product page for PA1931
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
PA1931 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-Nucleophosmin/NPM1 Antibody
Antibody type
Polyclonal
Description
Polyclonal antibody for B23/NPM1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. B23/NPM1 information: Molecular Weight: 32575 MW; Subcellular Localization: Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Vial size
100μg/vial
Concentration
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
NPM1 protein structure - PA1931 shown in red.