orb639938

antibody from Biorbyt
Targeting: SPTB
Provider product page for orb639938
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb639938 - Provider product page
Provider
Biorbyt
Product name
SPTB Antibody / Spectrin beta
Antibody type
Monoclonal
Description
Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
RG/26
Vial size
20 ug
Storage
Store the SPTB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
SPTB protein structure - orb639938 shown in red.