orb2634832

antibody from Biorbyt
Targeting: MED22 Med24, SRB6, SURF5
Provider product page for orb2634832
Western blot
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2634832 - Provider product page
Provider
Biorbyt
Product name
MED22 Antibody
Antibody type
Monoclonal
Description
Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-MED22-1E4
Vial size
100 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
MED22 protein structure - orb2634832 shown in red.