HTR3B

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]

Description

5-hydroxytryptamine receptor 3B

Protein family

FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins

Chromosome

11:q23.2 (113904677 - 113949078)

Ensembl ID

ENSG00000149305  (ver. 99.38)

Orthologs

Mouse Htr3b: ENSMUSG00000008590

UniProt

O95264

neXtProt

NX_O95264

Human splice variants
Mouse splice variants