BS7884

antibody from Bioworld Technology, Inc
Targeting: GTF2F2 BTF4, RAP30, TFIIF
Provider product page for BS7884
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7884 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GTF2F2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GTF2F2.
Description
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GTF2F2 protein structure - BS7884 shown in red.