AF2589

antibody from R&D Systems

Targeting: ARTN ENOVIN, EVN, NBN

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

AF2589

Provider

R&D Systems

Product name

Human Artemin Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human Artemin in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Artemin is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q5T4W7


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signalling.

Banerjee A, Wu ZS, Qian PX, Kang J, Liu DX, Zhu T, Lobie PE
PloS one 2012;7(11):e50098

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Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells.

Pandey V, Qian PX, Kang J, Perry JK, Mitchell MD, Yin Z, Wu ZS, Liu DX, Zhu T, Lobie PE
Endocrinology 2010 Mar;151(3):909-20

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Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma.

Kang J, Qian PX, Pandey V, Perry JK, Miller LD, Liu ET, Zhu T, Liu DX, Lobie PE
Oncogene 2010 Jun 3;29(22):3228-40

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Transcriptional activation of p53 by Pitx1.

Liu DX, Lobie PE
Cell death and differentiation 2007 Nov;14(11):1893-907