CABT-B10108

antibody from Creative Diagnostics

Targeting: DMAP1 DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B10108

Provider

Creative Diagnostics

Product name

Mouse anti-Human DMAP1 monoclonal antibody, clone 3H23

Antibody type

Monoclonal

Description

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3H23

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.