Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- MAB2387 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2387, RRID:AB_10688554
- Product name
- RAD51C monoclonal antibody, clone 2H11/6
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant RAD51C.
- Isotype
- IgG
- Antibody clone number
- 2H11/6
- Storage
- Store at 4°C. Do not freeze.
Submitted references Dysfunctional homologous recombination mediates genomic instability and progression in myeloma.
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.
Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression.
Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen.
Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC
Blood 2009 Mar 5;113(10):2290-7
Blood 2009 Mar 5;113(10):2290-7
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer PM, Powell S, Belmaaza A, Wouters B, Bristow RG
Cancer research 2008 Jan 15;68(2):605-14
Cancer research 2008 Jan 15;68(2):605-14
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.
Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK
The Journal of cell biology 2007 Feb 26;176(5):581-92
The Journal of cell biology 2007 Feb 26;176(5):581-92
Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression.
Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG
Cancer research 2004 Dec 1;64(23):8526-33
Cancer research 2004 Dec 1;64(23):8526-33
Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen.
Maacke H, Hundertmark C, Miska S, Voss M, Kalthoff H, Stürzbecher HW
Journal of cancer research and clinical oncology 2002 Apr;128(4):219-22
Journal of cancer research and clinical oncology 2002 Apr;128(4):219-22
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- RAD51C detected in HEK293 lysate using RAD51C monoclonal antibody, clone 2H11/6 (Cat # MAB2387). Photo courtesy of B.T. Bennett & K. Knight, University of Massachusetts Medical School.