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- Product number
- 10727-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10727-1-AP, RRID:AB_2278673
- Product name
- Ferritin light chain antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Ferritin light chain antibody (Cat. #10727-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis.
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Iron promotes ovarian cancer malignancy and advances platinum resistance by enhancing DNA repair via FTH1/FTL/POLQ/RAD51 axis.
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders.
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
LASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC.
Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis.
Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Plasticity changes in iron homeostasis in hibernating Daurian ground squirrels (Spermophilus dauricus) may counteract chronically inactive skeletal muscle atrophy.
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
A single-cell atlas of lung homeostasis reveals dynamic changes during development and aging.
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments.
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Identification of iron metabolism-related genes as prognostic indicators for papillary thyroid carcinoma: a retrospective study.
Sevoflurane inhibited reproductive function in male mice by reducing oxidative phosphorylation through inducing iron deficiency.
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression.
Exocarpium Citri Grandis alleviates the aggravation of NAFLD by mitigating lipid accumulation and iron metabolism disorders.
Overexpression of ferritin light chain as a poor prognostic factor for breast cancer.
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease.
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
Targeting ferroptosis by poly(acrylic) acid coated Mn(3)O(4) nanoparticles alleviates acute liver injury.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma.
Hemolytic iron regulation in traumatic brain injury and alcohol use.
Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells.
FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
l-Arginine-Modified CoWO(4) /FeWO(4) S-Scheme Heterojunction Enhances Ferroptosis against Solid Tumor.
Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis.
Regulation of Ferroptosis by Transcription Factor E2F1 and RB.
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury.
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Human hematopoietic stem cell vulnerability to ferroptosis.
Ferroptosis Is Involved in Sex-Specific Small Intestinal Toxicity in the Offspring of Adult Mice Exposed to Polystyrene Nanoplastics during Pregnancy.
Apolipoprotein E is required for brain iron homeostasis in mice.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
A ferroptosis-targeting ceria anchored halloysite as orally drug delivery system for radiation colitis therapy.
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
The Role of Iron in Atherosclerosis in Apolipoprotein E Deficient Mice.
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Electroacupuncture Reduces Cerebral Hemorrhage Injury in Rats by Improving Cerebral Iron Metabolism.
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Disordered Maternal and Fetal Iron Metabolism Occurs in Preterm Births in Human.
Ferrostatin-1 Ameliorates Liver Dysfunction via Reducing Iron in Thioacetamide-induced Acute Liver Injury in Mice.
TMT-Based Quantitative Proteomics Analysis Reveals the Panoramic Pharmacological Molecular Mechanism of β-Elemonic Acid Inhibition of Colorectal Cancer.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice.
Resistance to disuse-induced iron overload in Daurian ground squirrels (Spermophilus dauricus) during extended hibernation inactivity.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice.
Acute iron overload aggravates blood-brain barrier disruption and hemorrhagic transformation after transient focal ischemia in rats with hyperglycemia.
Remarkable Plasticity of Bone Iron Homeostasis in Hibernating Daurian Ground Squirrels (Spermophilus dauricus) May Be Involved in Bone Maintenance.
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
Longitudinal proteomics study of serum changes after allogeneic HSCT reveals potential markers of metabolic complications related to aGvHD.
Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases.
Central Nervous System Inflammation Induced by Lipopolysaccharide Up-Regulates Hepatic Hepcidin Expression by Activating the IL-6/JAK2/STAT3 Pathway in Mice.
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Hepcidin attenuates the iron-mediated secondary neuronal injury after intracerebral hemorrhage in rats.
Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14.
Fasting Increases Iron Export by Modulating Ferroportin 1 Expression Through the Ghrelin/GHSR1α/MAPK Pathway in the Liver.
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements.
Juxtacortical susceptibility changes in progressive multifocal leukoencephalopathy at the gray-white matter junction correlates with iron-enriched macrophages.
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
Apolipoprotein E deficiency induces a progressive increase in tissue iron contents with age in mice.
Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75(NTR) Ligand LM11A-31.
Identification and initial characterization of a potent inhibitor of ferroptosis.
GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis.
Cyclophosphamide induces a significant increase in iron content in the liver and spleen of mice.
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Angiotensin II down-regulates transferrin receptor 1 and ferroportin 1 expression in Neuro-2a cells via activation of type-1 receptor.
Identification of differentially expressed proteins associated with recurrence in ovarian endometriotic cysts.
Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron.
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Regulating ferroportin-1 and transferrin receptor-1 expression: A novel function of hydrogen sulfide.
Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess.
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation.
Fasting up-regulates ferroportin 1 expression via a Ghrelin/GHSR/MAPK signaling pathway.
Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells.
Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice.
Different Characteristics of Hepcidin Expression in IL-6+/+ and IL-6-/- Neurons and Astrocytes Treated with Lipopolysaccharides.
Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron.
Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
Effects of alpha-lipoic acid on expression of iron transport and storage proteins in BV-2 microglia cells.
Digital gene expression profiling analysis of duodenum transcriptomes in SD rats administered ferrous sulfate or ferrous glycine chelate by gavage.
Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin.
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure.
(Z)-ligustilide increases ferroportin1 expression and ferritin content in ischemic SH-SY5Y cells.
Effects of aspirin on expression of iron transport and storage proteins in BV-2 microglial cells.
Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma.
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Iron and neurodegeneration in the multiple sclerosis brain.
Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla.
Steinmaurer A, Riedl C, König T, Testa G, Köck U, Bauer J, Lassmann H, Höftberger R, Berger T, Wimmer I, Hametner S
Brain pathology (Zurich, Switzerland) 2024 Sep;34(5):e13240
Brain pathology (Zurich, Switzerland) 2024 Sep;34(5):e13240
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Wang X, Wang K, Mao W, Fan Z, Liu T, Hong R, Chen H, Pan C
Environmental research 2024 Oct 1;258:119483
Environmental research 2024 Oct 1;258:119483
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.
Feng L, Wang C, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Iron promotes ovarian cancer malignancy and advances platinum resistance by enhancing DNA repair via FTH1/FTL/POLQ/RAD51 axis.
Zhang Q, Chen C, Zou X, Wu W, Di Y, Li N, Fu A
Cell death & disease 2024 May 13;15(5):329
Cell death & disease 2024 May 13;15(5):329
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L
British journal of cancer 2024 Mar;130(5):755-768
British journal of cancer 2024 Mar;130(5):755-768
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13
BMC biotechnology 2024 Mar 8;24(1):13
Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders.
Zhang Y, Chen L, Xuan Y, Zhang L, Tian W, Zhu Y, Wang J, Wang X, Qiu J, Yu J, Tang M, He Z, Zhang H, Chen S, Shen Y, Wang S, Zhang R, Xu L, Ma X, Liao Y, Hu C
Cell reports 2024 Mar 26;43(3):113900
Cell reports 2024 Mar 26;43(3):113900
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Zhao J, Yi Z, Deng G, Li Y, Li J, Qin M, Wu C, Luo P, Ma S, Gao L
Free radical biology & medicine 2024 Jan;210:367-377
Free radical biology & medicine 2024 Jan;210:367-377
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Liu Y, Pang Z, Wang Y, Liu J, Wang G, Du J
Chemico-biological interactions 2024 Jan 5;387:110794
Chemico-biological interactions 2024 Jan 5;387:110794
Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling.
Deng G, Li J, Huang M, Li Y, Shi H, Wu C, Zhao J, Qin M, Liu C, Yang M, Wang Y, Zhang Y, Liao Y, Zhou C, Yang J, Xu Y, Liu B, Gao L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117320
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117320
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes.
Wang N, Zhao Y, Wu M, Li N, Yan C, Guo H, Li Q, Li Q, Wang Q
Molecular neurobiology 2024 Feb;61(2):1187-1201
Molecular neurobiology 2024 Feb;61(2):1187-1201
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Wang S, Xiong B, Tian Y, Hu Q, Jiang X, Zhang J, Chen L, Wang R, Li M, Zhou X, Zhang T, Ge H, Yu A
Molecular neurobiology 2024 Feb;61(2):1157-1174
Molecular neurobiology 2024 Feb;61(2):1157-1174
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Dan Z, Shi X, Shu C, Zhu R, Wang Y, Zhu H
Cellular signalling 2024 Feb;114:111001
Cellular signalling 2024 Feb;114:111001
LASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC.
Huang Y, Du J, Li D, He W, Liu Z, Liu L, Yang X, Cheng X, Chen R, Yang Y
Cancer cell international 2024 Feb 28;24(1):87
Cancer cell international 2024 Feb 28;24(1):87
Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis.
Li Y, Shen Q, Huang L, Li B, Zhang Y, Wang W, Zhao B, Gao W
Molecular neurobiology 2024 Apr;61(4):2151-2164
Molecular neurobiology 2024 Apr;61(4):2151-2164
Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Wu C, Li J, Jia H, Zhao J, Qin M, Shi H, Liu C, Lin J, Cai M, Gu Y, Liu B, Gao L
Journal of gastroenterology 2024 Apr;59(4):342-356
Journal of gastroenterology 2024 Apr;59(4):342-356
Plasticity changes in iron homeostasis in hibernating Daurian ground squirrels (Spermophilus dauricus) may counteract chronically inactive skeletal muscle atrophy.
Kong Y, Yin R, He Y, Pan F, Yang H, Wang H, Zhang J, Gao Y
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 2024 Apr;194(2):191-202
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 2024 Apr;194(2):191-202
Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis.
Wu X, Guan Y, Wang J, Song L, Zhang Y, Wang Y, Li Y, Qin L, He Q, Zhang T, Long B, Ji L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155340
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
A single-cell atlas of lung homeostasis reveals dynamic changes during development and aging.
Jia H, Chang Y, Chen Y, Chen X, Zhang H, Hua X, Xu M, Sheng Y, Zhang N, Cui H, Han L, Zhang J, Fu X, Song J
Communications biology 2024 Apr 8;7(1):427
Communications biology 2024 Apr 8;7(1):427
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
He YB, Han L, Wang C, Fang J, Shang Y, Cai HL, Zhou Q, Zhang ZZ, Chen SL, Li JY, Liu YL
Gene 2024 Apr 5;901:148168
Gene 2024 Apr 5;901:148168
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
Wang F, Wang L, Gan S, Feng S, Ouyang S, Wang X, Yuan S
Research (Washington, D.C.) 2023;6:0091
Research (Washington, D.C.) 2023;6:0091
Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway.
Jin X, He R, Lin Y, Liu J, Wang Y, Li Z, Liao Y, Yang S
Drug design, development and therapy 2023;17:3363-3383
Drug design, development and therapy 2023;17:3363-3383
A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments.
Zhang Z, Yu H, Wang Q, Ding Y, Wang Z, Zhao S, Bian T
Journal of inflammation research 2023;16:5647-5665
Journal of inflammation research 2023;16:5647-5665
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Gao Y, Zhang Z, Du J, Yang X, Wang X, Wen K, Sun X
Frontiers in pharmacology 2023;14:1148770
Frontiers in pharmacology 2023;14:1148770
Identification of iron metabolism-related genes as prognostic indicators for papillary thyroid carcinoma: a retrospective study.
Jin T, Ge L, Chen J, Wang W, Zhang L, Ge M
PeerJ 2023;11:e15592
PeerJ 2023;11:e15592
Sevoflurane inhibited reproductive function in male mice by reducing oxidative phosphorylation through inducing iron deficiency.
Zhang X, Zuo Y, Zhang J, Zhang D, Naeem M, Chang Y, Shi Z
Frontiers in cell and developmental biology 2023;11:1184632
Frontiers in cell and developmental biology 2023;11:1184632
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Liu W, Zhang S, Li Q, Wu Y, Jia X, Feng W, Li Z, Shi Y, Hou Q, Ma J, Liu Y, Gao P, Ganz T, Liu S
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression.
Zeng T, Li J, Xie L, Dong Z, Chen Q, Huang S, Xie S, Lai Y, Li J, Yan W, Wang Y, Xie Z, Hu C, Zhang J, Kuang S, Song Y, Gao L, Lv Z
Journal of neuroinflammation 2023 Sep 21;20(1):212
Journal of neuroinflammation 2023 Sep 21;20(1):212
Exocarpium Citri Grandis alleviates the aggravation of NAFLD by mitigating lipid accumulation and iron metabolism disorders.
Deng G, Liu C, Zhao J, Wang M, Li Y, Yang M, Ye H, Li J, Qin M, Wu C, Shi H, Liao Y, Zhou Z, Zhang S, Lam Yung KK, Gao L
Journal of ethnopharmacology 2023 Sep 15;313:116559
Journal of ethnopharmacology 2023 Sep 15;313:116559
Overexpression of ferritin light chain as a poor prognostic factor for breast cancer.
Tang C, Zhang B, Yang Y, Lin Z, Liu Y
Molecular biology reports 2023 Oct;50(10):8097-8109
Molecular biology reports 2023 Oct;50(10):8097-8109
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Dong T, Fan X, Zheng N, Yan K, Hou T, Peng L, Ci X
British journal of pharmacology 2023 Oct;180(19):2532-2549
British journal of pharmacology 2023 Oct;180(19):2532-2549
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Liu H, He Y, Gao X, Li T, Qiao B, Tang L, Lan J, Su Q, Ruan Z, Tang Z, Hu L
Mycotoxin research 2023 Nov;39(4):437-451
Mycotoxin research 2023 Nov;39(4):437-451
Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease.
Deng GH, Wu CF, Li YJ, Shi H, Zhong WC, Hong MK, Li JJ, Zhao JM, Liu C, Qin MC, Zeng ZY, Zhang WM, Yung KKL, Lv ZP, Gao L
Military Medical Research 2023 Nov 8;10(1):53
Military Medical Research 2023 Nov 8;10(1):53
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
Gao S, Gao S, Wang Y, Li N, Yang Z, Yao H, Chen Y, Cheng Y, Zhong Y, Shen X
International journal of molecular sciences 2023 Nov 29;24(23)
International journal of molecular sciences 2023 Nov 29;24(23)
Targeting ferroptosis by poly(acrylic) acid coated Mn(3)O(4) nanoparticles alleviates acute liver injury.
Shan X, Li J, Liu J, Feng B, Zhang T, Liu Q, Ma H, Wu H, Wu H
Nature communications 2023 Nov 21;14(1):7598
Nature communications 2023 Nov 21;14(1):7598
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
Li H, Deng C, Zhu N, Zhang C, Zeng Q, Qin L
Bioorganic chemistry 2023 May;134:106454
Bioorganic chemistry 2023 May;134:106454
G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration.
Li S, Liao Z, Yin H, Liu O, Hua W, Wu X, Zhang Y, Gao Y, Yang C
Cell proliferation 2023 Mar;56(3):e13368
Cell proliferation 2023 Mar;56(3):e13368
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Yao B, Cai Y, Wan L, Deng J, Zhao L, Wang W, Han Z
The journal of gene medicine 2023 Jun;25(6):e3488
The journal of gene medicine 2023 Jun;25(6):e3488
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma.
Wang M, Zeng G, Xiong B, Zhu X, Guo J, Chen D, Zhang S, Luo M, Guo L, Cai L
Biochemical pharmacology 2023 Jun;212:115554
Biochemical pharmacology 2023 Jun;212:115554
Hemolytic iron regulation in traumatic brain injury and alcohol use.
Agas A, Ravula AR, Ma X, Cheng Y, Belfield KD, Haorah J
Alcohol (Fayetteville, N.Y.) 2023 Jun;109:1-12
Alcohol (Fayetteville, N.Y.) 2023 Jun;109:1-12
Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells.
He J, Abikoye AM, McLaughlin BP, Middleton RS, Sheldon R, Jones RG, Schafer ZT
iScience 2023 Jun 16;26(6):106827
iScience 2023 Jun 16;26(6):106827
FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.
Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z
Redox biology 2023 Jul;63:102727
Redox biology 2023 Jul;63:102727
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Wu H, Liu Q, Shan X, Gao W, Chen Q
Autophagy 2023 Jul;19(7):2062-2077
Autophagy 2023 Jul;19(7):2062-2077
l-Arginine-Modified CoWO(4) /FeWO(4) S-Scheme Heterojunction Enhances Ferroptosis against Solid Tumor.
Yang Z, Yang C, Yang D, Zhang Y, Yang Q, Qu F, Guo W
Advanced healthcare materials 2023 Jul;12(18):e2203092
Advanced healthcare materials 2023 Jul;12(18):e2203092
Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis.
Yuan X, Li L, Zhang Y, Ai R, Li D, Dou Y, Hou M, Zhao D, Zhao S, Nan Y
Lipids in health and disease 2023 Jul 8;22(1):99
Lipids in health and disease 2023 Jul 8;22(1):99
Regulation of Ferroptosis by Transcription Factor E2F1 and RB.
Kuganesan N, Dlamini S, Tillekeratne VL, Taylor WR
Research square 2023 Jan 30;
Research square 2023 Jan 30;
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Jiang Z, Sun H, Miao J, Sheng Q, Xu J, Gao Z, Zhang X, Song Y, Chen K
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Biochemical and biophysical research communications 2023 Jan 15;640:183-191
Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury.
Mei T, Wu J, Wu K, Zhao M, Luo J, Liu X, Shang B, Xu W, Yang Z, Lai Y, Liu C, Gong H, Gao X, Zhuo Y, Lin M, Zhao L
Annals of translational medicine 2023 Jan 15;11(1):3
Annals of translational medicine 2023 Jan 15;11(1):3
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Gu W, Hou T, Zhou H, Zhu L, Zhu W, Wang Y
International immunopharmacology 2023 Feb;115:109658
International immunopharmacology 2023 Feb;115:109658
Human hematopoietic stem cell vulnerability to ferroptosis.
Zhao J, Jia Y, Mahmut D, Deik AA, Jeanfavre S, Clish CB, Sankaran VG
Cell 2023 Feb 16;186(4):732-747.e16
Cell 2023 Feb 16;186(4):732-747.e16
Ferroptosis Is Involved in Sex-Specific Small Intestinal Toxicity in the Offspring of Adult Mice Exposed to Polystyrene Nanoplastics during Pregnancy.
Tang J, Bu W, Hu W, Zhao Z, Liu L, Luo C, Wang R, Fan S, Yu S, Wu Q, Wang X, Zhao X
ACS nano 2023 Feb 14;17(3):2440-2449
ACS nano 2023 Feb 14;17(3):2440-2449
Apolipoprotein E is required for brain iron homeostasis in mice.
Ma J, Guo Q, Shen MQ, Li W, Zhong QX, Qian ZM
Redox biology 2023 Aug;64:102779
Redox biology 2023 Aug;64:102779
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
A ferroptosis-targeting ceria anchored halloysite as orally drug delivery system for radiation colitis therapy.
Feng Y, Luo X, Li Z, Fan X, Wang Y, He RR, Liu M
Nature communications 2023 Aug 22;14(1):5083
Nature communications 2023 Aug 22;14(1):5083
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Xie J, Lv H, Liu X, Xia Z, Li J, Hong E, Ding B, Zhang W, Chen Y
Free radical biology & medicine 2023 Apr;199:67-80
Free radical biology & medicine 2023 Apr;199:67-80
Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth.
Dai Y, Zhu C, Xiao W, Huang K, Wang X, Shi C, Lin D, Zhang H, Liu X, Peng B, Gao Y, Liu CH, Ge B, Kaufmann SH, Feng CG, Chen X, Cai Y
The Journal of clinical investigation 2023 Apr 17;133(8)
The Journal of clinical investigation 2023 Apr 17;133(8)
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
The Role of Iron in Atherosclerosis in Apolipoprotein E Deficient Mice.
Ma J, Ma HM, Shen MQ, Wang YY, Bao YX, Liu Y, Ke Y, Qian ZM
Frontiers in cardiovascular medicine 2022;9:857933
Frontiers in cardiovascular medicine 2022;9:857933
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Gong H, Gao M, Lin Y, Liu J, Hu Z, Liu J
Oxidative medicine and cellular longevity 2022;2022:7843863
Oxidative medicine and cellular longevity 2022;2022:7843863
Electroacupuncture Reduces Cerebral Hemorrhage Injury in Rats by Improving Cerebral Iron Metabolism.
Chen Q, Song W, Tang Y, Tang Y, Kang Y, Zhu L
Mediators of inflammation 2022;2022:6943438
Mediators of inflammation 2022;2022:6943438
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Han S, Lin F, Qi Y, Liu C, Zhou L, Xia Y, Chen K, Xing J, Liu Z, Yu W, Zhang Y, Zhou X, Rao T, Cheng F
Oxidative medicine and cellular longevity 2022;2022:3846217
Oxidative medicine and cellular longevity 2022;2022:3846217
Disordered Maternal and Fetal Iron Metabolism Occurs in Preterm Births in Human.
Liu W, Wu Y, Zhang N, Liu S, Zhou L
Disease markers 2022;2022:1664474
Disease markers 2022;2022:1664474
Ferrostatin-1 Ameliorates Liver Dysfunction via Reducing Iron in Thioacetamide-induced Acute Liver Injury in Mice.
Jiang H, Zhang X, Yang W, Li M, Wang G, Luo Q
Frontiers in pharmacology 2022;13:869794
Frontiers in pharmacology 2022;13:869794
TMT-Based Quantitative Proteomics Analysis Reveals the Panoramic Pharmacological Molecular Mechanism of β-Elemonic Acid Inhibition of Colorectal Cancer.
Xia Y, Yang J, Li C, Hao X, Fan H, Zhao Y, Tang J, Wan X, Lian S, Yang J
Frontiers in pharmacology 2022;13:830328
Frontiers in pharmacology 2022;13:830328
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Feng W, Xiao Y, Zhao C, Zhang Z, Liu W, Ma J, Ganz T, Zhang J, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2202679
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Hou Y, Wang S, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Yang G
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Fu F, Lai Q, Hu J, Zhang L, Zhu X, Kou J, Yu B, Li F
Antioxidants (Basel, Switzerland) 2022 Mar 18;11(3)
Antioxidants (Basel, Switzerland) 2022 Mar 18;11(3)
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice.
Yan PJ, Ren ZX, Shi ZF, Wan CL, Han CJ, Zhu LS, Li NN, Waddington JL, Zhen XC
Acta pharmacologica Sinica 2022 Jul;43(7):1686-1698
Acta pharmacologica Sinica 2022 Jul;43(7):1686-1698
Resistance to disuse-induced iron overload in Daurian ground squirrels (Spermophilus dauricus) during extended hibernation inactivity.
Yin R, Zhang J, Xu S, Kong Y, Wang H, Gao Y
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2022 Jan;257:110650
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2022 Jan;257:110650
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice.
Zheng J, Wang JJ, Ma HM, Shen MQ, Qian ZM, Bao YX
Redox report : communications in free radical research 2022 Dec;27(1):119-127
Redox report : communications in free radical research 2022 Dec;27(1):119-127
Acute iron overload aggravates blood-brain barrier disruption and hemorrhagic transformation after transient focal ischemia in rats with hyperglycemia.
Wu Q, Wei C, Guo S, Liu J, Xiao H, Wu S, Wu B, Liu M
IBRO neuroscience reports 2022 Dec;13:87-95
IBRO neuroscience reports 2022 Dec;13:87-95
Remarkable Plasticity of Bone Iron Homeostasis in Hibernating Daurian Ground Squirrels (Spermophilus dauricus) May Be Involved in Bone Maintenance.
He Y, Kong Y, Yin R, Yang H, Zhang J, Wang H, Gao Y
International journal of molecular sciences 2022 Dec 13;23(24)
International journal of molecular sciences 2022 Dec 13;23(24)
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
Hu J, Gu W, Ma N, Fan X, Ci X
British journal of pharmacology 2022 Aug;179(15):3991-4009
British journal of pharmacology 2022 Aug;179(15):3991-4009
Longitudinal proteomics study of serum changes after allogeneic HSCT reveals potential markers of metabolic complications related to aGvHD.
Wong SY, Kato S, Rodenburg F, Tojo A, Hayashi N
Scientific reports 2022 Aug 17;12(1):14002
Scientific reports 2022 Aug 17;12(1):14002
Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases.
Singh LP, Yumnamcha T, Devi TS
JOJ ophthalmology 2021;8(5):77-85
JOJ ophthalmology 2021;8(5):77-85
Central Nervous System Inflammation Induced by Lipopolysaccharide Up-Regulates Hepatic Hepcidin Expression by Activating the IL-6/JAK2/STAT3 Pathway in Mice.
Zhang F, Zhao P, Qian Z, Zhong M
Frontiers in nutrition 2021;8:649640
Frontiers in nutrition 2021;8:649640
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
He Y, Fang D, Liang T, Pang H, Nong Y, Tang L, Yang Z, Lu C, Han X, Zhao S, Mo S, Meng Y, Han C, Peng T
Annals of translational medicine 2021 Oct;9(20):1535
Annals of translational medicine 2021 Oct;9(20):1535
GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis.
Wang L, Ouyang S, Li B, Wu H, Wang F
Cell death discovery 2021 Nov 3;7(1):334
Cell death discovery 2021 Nov 3;7(1):334
Hepcidin attenuates the iron-mediated secondary neuronal injury after intracerebral hemorrhage in rats.
Yang G, Qian C, Zhang C, Bao Y, Liu MY, Jiang F, Li W, Liu Y, Ke Y, Qian ZM
Translational research : the journal of laboratory and clinical medicine 2021 Mar;229:53-68
Translational research : the journal of laboratory and clinical medicine 2021 Mar;229:53-68
Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14.
Prajapati M, Conboy HL, Hojyo S, Fukada T, Budnik B, Bartnikas TB
The Journal of biological chemistry 2021 Jul;297(1):100835
The Journal of biological chemistry 2021 Jul;297(1):100835
Fasting Increases Iron Export by Modulating Ferroportin 1 Expression Through the Ghrelin/GHSR1α/MAPK Pathway in the Liver.
Luo Q, Hu J, Yang G, Yuan X, Chen Z, Wang D, Lu Y, Zhu L, Wang G
Biological trace element research 2021 Jan;199(1):267-277
Biological trace element research 2021 Jan;199(1):267-277
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Lai Q, Yuan G, Shen L, Zhang L, Fu F, Liu Z, Zhang Y, Kou J, Liu S, Yu B, Li F
Basic research in cardiology 2021 Jan 23;116(1):3
Basic research in cardiology 2021 Jan 23;116(1):3
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements.
Zhang Q, Lu XM, Zhang M, Yang CY, Lv SY, Li SF, Zhong CY, Geng SS
Scientific reports 2021 Jan 14;11(1):1347
Scientific reports 2021 Jan 14;11(1):1347
Juxtacortical susceptibility changes in progressive multifocal leukoencephalopathy at the gray-white matter junction correlates with iron-enriched macrophages.
Mahajan KR, Amin M, Poturalski M, Lee J, Herman D, Zheng Y, Androjna C, Howell M, Fox RJ, Trapp BD, Jones SE, Nakamura K, Ontaneda D
Multiple sclerosis (Houndmills, Basingstoke, England) 2021 Dec;27(14):2159-2169
Multiple sclerosis (Houndmills, Basingstoke, England) 2021 Dec;27(14):2159-2169
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
Wang K, Chen X, Zuyi W, Chen L, Fu W
Environmental toxicology 2021 Aug;36(8):1654-1663
Environmental toxicology 2021 Aug;36(8):1654-1663
Apolipoprotein E deficiency induces a progressive increase in tissue iron contents with age in mice.
Ma J, Qian C, Bao Y, Liu MY, Ma HM, Shen MQ, Li W, Wang JJ, Bao YX, Liu Y, Ke Y, Qian ZM
Redox biology 2021 Apr;40:101865
Redox biology 2021 Apr;40:101865
Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75(NTR) Ligand LM11A-31.
Simmons DA, Mills BD, Butler Iii RR, Kuan J, McHugh TLM, Akers C, Zhou J, Syriani W, Grouban M, Zeineh M, Longo FM
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Apr;18(2):1039-1063
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Apr;18(2):1039-1063
Identification and initial characterization of a potent inhibitor of ferroptosis.
Kuganesan N, Dlamini S, McDaniel J, Tillekeratne VLM, Taylor WR
Journal of cellular biochemistry 2021 Apr;122(3-4):413-424
Journal of cellular biochemistry 2021 Apr;122(3-4):413-424
GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis.
Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K, Tang N
Cell death & disease 2021 Apr 30;12(5):426
Cell death & disease 2021 Apr 30;12(5):426
Cyclophosphamide induces a significant increase in iron content in the liver and spleen of mice.
Sheng Y, Chen YJ, Qian ZM, Zheng J, Liu Y
Human & experimental toxicology 2020 Jul;39(7):973-983
Human & experimental toxicology 2020 Jul;39(7):973-983
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574
Cell death & disease 2020 Jul 24;11(7):574
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
Angiotensin II down-regulates transferrin receptor 1 and ferroportin 1 expression in Neuro-2a cells via activation of type-1 receptor.
Chen YJ, Qian ZM, Sheng Y, Zheng J, Liu Y
Neuroscience letters 2020 Jan 18;716:134684
Neuroscience letters 2020 Jan 18;716:134684
Identification of differentially expressed proteins associated with recurrence in ovarian endometriotic cysts.
Zhu G, Kong J, Fu X, Liu F, Huang H, Hong L, Wang K
Systems biology in reproductive medicine 2020 Feb;66(1):59-69
Systems biology in reproductive medicine 2020 Feb;66(1):59-69
Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron.
Li S, Qian ZM, Xu G, Zheng J, Wu Y
Bioscience reports 2020 Apr 30;40(4)
Bioscience reports 2020 Apr 30;40(4)
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Gao W, Wang W, Liu G, Zhang J, Yang J, Deng Z
Metabolic brain disease 2019 Feb;34(1):319-329
Metabolic brain disease 2019 Feb;34(1):319-329
Regulating ferroportin-1 and transferrin receptor-1 expression: A novel function of hydrogen sulfide.
Zhang MW, Yang G, Zhou YF, Qian C, Mu MD, Ke Y, Qian ZM
Journal of cellular physiology 2019 Apr;234(4):3158-3169
Journal of cellular physiology 2019 Apr;234(4):3158-3169
Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess.
Mercadante CJ, Prajapati M, Parmar JH, Conboy HL, Dash ME, Pettiglio MA, Herrera C, Bu JT, Stopa EG, Mendes P, Bartnikas TB
Haematologica 2019 Apr;104(4):678-689
Haematologica 2019 Apr;104(4):678-689
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, Li H
Cell & bioscience 2018;8:41
Cell & bioscience 2018;8:41
Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation.
Huang T, Sun Y, Li Y, Wang T, Fu Y, Li C, Li C
Oxidative medicine and cellular longevity 2018;2018:4928703
Oxidative medicine and cellular longevity 2018;2018:4928703
Fasting up-regulates ferroportin 1 expression via a Ghrelin/GHSR/MAPK signaling pathway.
Luo QQ, Zhou YF, Chen MY, Liu L, Ma J, Zhang MW, Zhang FL, Ke Y, Qian ZM
Journal of cellular physiology 2018 Jan;233(1):30-37
Journal of cellular physiology 2018 Jan;233(1):30-37
Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells.
Huang SN, Ruan HZ, Chen MY, Zhou G, Qian ZM
Neuroscience letters 2018 Jan 1;662:1-5
Neuroscience letters 2018 Jan 1;662:1-5
Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice.
Zhang MW, Zhao P, Yung WH, Sheng Y, Ke Y, Qian ZM
Aging 2018 Dec 16;10(12):3834-3850
Aging 2018 Dec 16;10(12):3834-3850
Different Characteristics of Hepcidin Expression in IL-6+/+ and IL-6-/- Neurons and Astrocytes Treated with Lipopolysaccharides.
Ma J, Zhang FL, Zhou G, Bao YX, Shen Y, Qian ZM
Neurochemical research 2018 Aug;43(8):1624-1630
Neurochemical research 2018 Aug;43(8):1624-1630
Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron.
Zhou YF, Zhang C, Yang G, Qian ZM, Zhang MW, Ma J, Zhang FL, Ke Y
Frontiers in physiology 2017;8:332
Frontiers in physiology 2017;8:332
Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner HL, Lassmann H
Brain : a journal of neurology 2017 Jul 1;140(7):1900-1913
Brain : a journal of neurology 2017 Jul 1;140(7):1900-1913
Effects of alpha-lipoic acid on expression of iron transport and storage proteins in BV-2 microglia cells.
Chen P, Li FM, Zhou YF, Qian C, Li J, Jiang LR, Qian ZM
Pharmacological reports : PR 2017 Feb;69(1):1-5
Pharmacological reports : PR 2017 Feb;69(1):1-5
Digital gene expression profiling analysis of duodenum transcriptomes in SD rats administered ferrous sulfate or ferrous glycine chelate by gavage.
Zhuo Z, Fang S, Hu Q, Huang D, Feng J
Scientific reports 2016 Nov 30;6:37923
Scientific reports 2016 Nov 30;6:37923
Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin.
Xue D, Zhou C, Shi Y, Lu H, Xu R, He X
Oncotarget 2016 Nov 29;7(48):78804-78812
Oncotarget 2016 Nov 29;7(48):78804-78812
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Pettiglio MA, Herrera C, Foster ML, Dorman DC, Bartnikas TB
Data in brief 2016 Mar;6:989-97
Data in brief 2016 Mar;6:989-97
(Z)-ligustilide increases ferroportin1 expression and ferritin content in ischemic SH-SY5Y cells.
Zhang YT, Li FM, Guo YZ, Jiang LR, Ma J, Ke Y, Qian ZM
European journal of pharmacology 2016 Dec 5;792:48-53
European journal of pharmacology 2016 Dec 5;792:48-53
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Xu YX, Du F, Jiang LR, Gong J, Zhou YF, Luo QQ, Qian ZM, Ke Y
Neurochemistry international 2015 Dec;91:72-7
Neurochemistry international 2015 Dec;91:72-7
Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma.
Chen RX, Song HY, Dong YY, Hu C, Zheng QD, Xue TC, Liu XH, Zhang Y, Chen J, Ren ZG, Liu YK, Cui JF
PloS one 2014;9(3):e88543
PloS one 2014;9(3):e88543
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
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Nature cell biology 2014 Nov;16(11):1069-79
Nature cell biology 2014 Nov;16(11):1069-79
Iron and neurodegeneration in the multiple sclerosis brain.
Hametner S, Wimmer I, Haider L, Pfeifenbring S, Brück W, Lassmann H
Annals of neurology 2013 Dec;74(6):848-61
Annals of neurology 2013 Dec;74(6):848-61
Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla.
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Brain : a journal of neurology 2011 Dec;134(Pt 12):3602-15
Brain : a journal of neurology 2011 Dec;134(Pt 12):3602-15
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- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 10727-1-AP(FTL antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-FTL (IP:10727-1-AP, 3ug; Detection:10727-1-AP 1:1000) with mouse liver tissue lysate 12500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Ferritin light chain antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Ferritin light chain. This antibody recognizes human,mouse,rat antigen. The Ferritin light chain antibody has been validated for the following applications: ELISA, WB, IP, IHC analysis.
