51034-1-AP

antibody from Proteintech Group

Targeting: HSF1 HSTF1

Provider product page for 51034-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

Submit

Product number: 51034-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#51034-1-AP, RRID:AB_2120269
Product name: HSF1 antibody
Antibody type: Polyclonal
Description: HSF1 antibody (Cat. #51034-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

HSF1 protein structure - 51034-1-AP shown in red.

Submitted references Intronic VNTRs downregulate expression of HSF1 and confer genetic risk of essential tremor.

Bi H, Wan Y, Zhao R, Pan S, Luan M, Wu W, Qiu Y, Yu J, Sun Y, Wei L, Chen J, Li F, Sun W, Wang L, Wang X, Zhao W, Wang D, Tuo H, Zhang Y, Zhang W, Huang Y, Yuan Y, Hong D, Wang Z, Deng J
Brain : a journal of neurology 2025 Nov 4;148(11):4098-4111

Optically controllable nanoregulators enable tumor-specific pro-ferroptosis lipometabolic reprogramming for in-situ adjuvant-free vaccination.

Li M, Li Y, Yao X, Liu Y, Cai K, Yang H, Luo Z
Biomaterials 2025 Jun;317:123096

Inhibition of SIRT1/HSF1 pathway contributes to doxorubicin-induced nephrotoxicity in ovarian tumor-bearing mice.

Chen M, Zhao Y, Hu S, Yuan JB, Xie KJ, Cai SN, Zhu XY, Du JK, Xu PB
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1572-1588

Bilateral Synergistic Effects of Phototherapy-Based NIR-II Absorption Photosensitizer for Allergic Rhinitis.

Shao T, Han L, Xie Y, Shi Z, Yang Q, Liu A, Liu Y, Chen L, Huang J, Peng B, Bai H, Chen H, Li L, Bian K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jun;21(22):e2412249

Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.

Ma L, Gao Y, Chen J, Hai D, Yu J, Tang S, Liu N, Liu Y
Journal of ethnopharmacology 2025 Jul 24;351:120072

HSF1 and CPSF1 affect milk fat and protein synthesis by regulating the AKT/mTOR signaling pathway.

Chen Z, Zhang X, Teng J, Jiang L, Zhang Q
Journal of animal science 2025 Jan 4;103

Heat shock transcription factor 1 facilitates liver cancer progression by driving super-enhancer-mediated transcription of MYCN.

Liu Y, Shi Q, Su Y, Chen Z, He X
Cancer medicine 2024 Sep;13(17):e70157

Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.

Zhang X, Xu Y, Fan M, Lv X, Long J, Yang R, Zhang R, Liu Z, Gu J, Wu P, Wang C
Journal of ethnopharmacology 2024 Mar 1;321:117483

Protective effects of L-theanine and dihydromyricetin on reproductive function in male mice under heat stress.

Yang D, Xu K, Wang W, Chen P, Liu C, Liu S, Xu W, Xiao W
Food & function 2024 Jul 1;15(13):7093-7107

Disrupted HSF1 regulation in normal and exceptional brain aging.

Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
Biogerontology 2024 Feb;25(1):147-160

RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation.

Shen CL, Tsai YY, Chou SJ, Chang YM, Tarn WY
Communications biology 2024 Dec 30;7(1):1712

The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity.

Fleming AC, Rao NR, Wright M, Savas JN, Kiskinis E
bioRxiv : the preprint server for biology 2024 Dec 1;

USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization.

Wang J, Xiang Y, Xie Z, Fan M, Fang S, Wan H, Zhao R, Zeng F, Hua Q
Cancers 2023 Sep 1;15(17)

Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.

Zhang J, Dong Y, Liu X, Jin H, Wang S, An N, Wang L
International journal of pharmaceutics 2023 Oct 15;645:123389

Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.

Li L, Li D, Sun D, Zhang X, Lei W, Wu M, Huang Q, Nian X, Dai W, Lu X, Zhou Z, Zhu Y, Xiao Y, Zhang L, Mo W, Liu Z, Zhang L
Developmental cell 2023 Nov 6;58(21):2275-2291.e6

Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.

Cui D, Wang Z, Dang Q, Wang J, Qin J, Song J, Zhai X, Zhou Y, Zhao L, Lu G, Liu H, Liu G, Liu R, Shao C, Zhang X, Liu Z
Nature communications 2023 Nov 3;14(1):7032

Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.

Zhao J, Yang S, Lv C, Liu Y
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052

Z-DNA binding protein 1 promotes heatstroke-induced cell death.

Yuan F, Cai J, Wu J, Tang Y, Zhao K, Liang F, Li F, Yang X, He Z, Billiar TR, Wang H, Su L, Lu B
Science (New York, N.Y.) 2022 May 6;376(6593):609-615

A simplified and sensitive immunoprecipitation approach for the analysis of HSF1 in murine liver tissue.

Trivedi R, Tripathi JK, Knopf B, Manocha GD, Jurivich DA
MethodsX 2021;8:101478

BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease.

Martin TG, Tawfik S, Moravec CS, Pak TR, Kirk JA
American journal of physiology. Heart and circulatory physiology 2021 Jun 1;320(6):H2339-H2350

Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cells In Vitro.

Bai H, Li T, Yu Y, Zhou N, Kou H, Guo Y, Yang L, Yan P
Cells 2021 Jan 28;10(2)

Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice.

Trivedi R, Knopf B, Tripathi JK, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA
GeroScience 2021 Aug;43(4):1921-1934

The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction.

Gomez-Paredes C, Mason MA, Taxy BA, Papadopoulou AS, Paganetti P, Bates GP
Scientific reports 2021 Apr 27;11(1):9117

Multifactorial Attenuation of the Murine Heat Shock Response With Age.

Jurivich DA, Manocha GD, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Sep 25;75(10):1846-1852

Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC.

Guo Y, Wang J, Zhou K, Lv J, Wang L, Gao S, Keller ET, Zhang ZS, Wang Q, Yao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7927-7940

HSF1 mediated stress response of heavy metals.

Steurer C, Eder N, Kerschbaum S, Wegrostek C, Gabriel S, Pardo N, Ortner V, Czerny T, Riegel E
PloS one 2018;13(12):e0209077

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Jurkat cells were subjected to SDS PAGE followed by western blot with 51034-1-AP(HSF1 antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The HSF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSF1. This antibody recognizes human, mouse, rat antigen. The HSF1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Appendix: 51034-1-AP.pdf

: Show more