Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- 24758-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- SMC4 antibody
- Antibody type
- Polyclonal
- Description
- SMC4 antibody (Cat. #24758-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SMC4/SMAD3/NF-κB axis drives cervical cancer progression and radioresistance via DNA damage repair and immune modulation.
NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma.
SMC4 serves as a potential marker for the diagnosis and prognosis of colon adenocarcinoma.
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures.
Cryo-Electron Tomography and Proteomics studies of centrosomes from differentiated quiescent thymocytes.
Transcriptional profiling of rat skeletal muscle hypertrophy under restriction of blood flow.
Wu H, Yu Y, Wang W, Xu Q
Journal of translational medicine 2026 Mar 9;24(1)
Journal of translational medicine 2026 Mar 9;24(1)
NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma.
Li G, Zhao Y, He Y, Qian Z, Li X, Song Z, Liu Z
Frontiers in oncology 2025;15:1624370
Frontiers in oncology 2025;15:1624370
SMC4 serves as a potential marker for the diagnosis and prognosis of colon adenocarcinoma.
Yang D, Cheng W, Liu Y, Ma L, Sun Y, Wang H, Liu H, Nan L, Yang Y, Wang X
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241286565
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241286565
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Sun X, He L, Liu H, Thorne RF, Zeng T, Liu L, Zhang B, He M, Huang Y, Li M, Gao E, Ma M, Cheng C, Meng F, Lang C, Li H, Xiong W, Pan S, Ren D, Dang B, Yang Y, Wu M, Liu L
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures.
Gönenc II, Wolff A, Schmidt J, Zibat A, Müller C, Cyganek L, Argyriou L, Räschle M, Yigit G, Wollnik B
Human molecular genetics 2022 Jul 7;31(13):2185-2193
Human molecular genetics 2022 Jul 7;31(13):2185-2193
Cryo-Electron Tomography and Proteomics studies of centrosomes from differentiated quiescent thymocytes.
Busselez J, Chichón FJ, Rodríguez MJ, Alpízar A, Gharbi SI, Franch M, Melero R, Paradela A, Carrascosa JL, Carazo JM
Scientific reports 2019 May 10;9(1):7187
Scientific reports 2019 May 10;9(1):7187
Transcriptional profiling of rat skeletal muscle hypertrophy under restriction of blood flow.
Xu S, Liu X, Chen Z, Li G, Chen Q, Zhou G, Ma R, Yao X, Huang X
Gene 2016 Dec 15;594(2):229-237
Gene 2016 Dec 15;594(2):229-237
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The SMC4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SMC4. This antibody recognizes human antigen. The SMC4 antibody has been validated for the following applications: ELISA, IHC, IF, WB analysis.