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- Antigen structure
- References [12]
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- Western blot [1]
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- Product number
- 12463-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12463-1-AP, RRID:AB_2133821
- Product name
- KPNA4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KPNA4 antibody (Cat. #12463-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Enolase 1 suppresses influenza A virus replication by blocking the nuclear import of the viral ribonucleoprotein complex.
YWHAZ downregulated innate immune responses to RNA viruses by inhibiting the IRF3 signaling pathway.
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis.
Oncometabolite fumarate facilitates PD-L1 expression and immune evasion in clear cell renal cell carcinoma.
Direct observation of importin α family member KPNA1 in axonal transport with or without a schizophrenia-related mutation.
MERS-CoV-nsp5 expression in human epithelial BEAS 2b cells attenuates type I interferon production by inhibiting IRF3 nuclear translocation.
Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2.
Age-dependent changes in nuclear-cytoplasmic signaling in skeletal muscle.
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.
Reanalysis of microRNA expression profiles identifies novel biomarkers for hepatocellular carcinoma prognosis.
Kong X, Liu J, Zhu Q, Xu S
Cellular and molecular life sciences : CMLS 2026 Feb 25;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 25;83(1)
YWHAZ downregulated innate immune responses to RNA viruses by inhibiting the IRF3 signaling pathway.
Li S, Han J, Wang H, Hou J, Wang L, Hou Z, Zhang Y, Dou X, Xie J, Li H, Li X, Feng R
mSphere 2026 Apr 28;11(4):e0003826
mSphere 2026 Apr 28;11(4):e0003826
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis.
Atwal MS, Nimac J, Čerček U, Goesch SR, Goesch HR, Tziortzouda P, Ercolani T, Zatorska A, Pasha T, Carre I, Mitchell J, Troakes C, Tummers B, Župunski V, Rogelj B, Hortobágyi T, Hirth F
Frontiers in neuroscience 2025;19:1558227
Frontiers in neuroscience 2025;19:1558227
Oncometabolite fumarate facilitates PD-L1 expression and immune evasion in clear cell renal cell carcinoma.
Gao Y, Fan S, Sun X, Li J, Dai Y, Li H, Ma H, Xu Y, Lv L
Cell death & disease 2025 Jun 3;16(1):432
Cell death & disease 2025 Jun 3;16(1):432
Direct observation of importin α family member KPNA1 in axonal transport with or without a schizophrenia-related mutation.
Mizuno K, Sugahara M, Kutomi O, Kato R, Itoh T, Fujita S, Yamada M
The Journal of biological chemistry 2025 Apr;301(4):108343
The Journal of biological chemistry 2025 Apr;301(4):108343
MERS-CoV-nsp5 expression in human epithelial BEAS 2b cells attenuates type I interferon production by inhibiting IRF3 nuclear translocation.
Zhang Y, Kandwal S, Fayne D, Stevenson NJ
Cellular and molecular life sciences : CMLS 2024 Oct 12;81(1):433
Cellular and molecular life sciences : CMLS 2024 Oct 12;81(1):433
Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2.
Nakanishi A, Okumura H, Hashita T, Yamashita A, Nishimura Y, Watanabe C, Kamimura S, Hayashi S, Murakami S, Ito K, Iwao T, Ikeda A, Hirose T, Sunazuka T, Tanaka Y, Matsunaga T
Viruses 2022 Nov 8;14(11)
Viruses 2022 Nov 8;14(11)
Age-dependent changes in nuclear-cytoplasmic signaling in skeletal muscle.
Iyer SR, Hsia RC, Folker ES, Lovering RM
Experimental gerontology 2021 Jul 15;150:111338
Experimental gerontology 2021 Jul 15;150:111338
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Zhuo Y, Guo Z, Ba T, Zhang C, He L, Zeng C, Dai H
Virologica Sinica 2021 Apr;36(2):176-186
Virologica Sinica 2021 Apr;36(2):176-186
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.
Zhu Y, Vidaurre OG, Adula KP, Kezunovic N, Wentling M, Huntley GW, Casaccia P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 2;37(31):7547-7559
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 2;37(31):7547-7559
Reanalysis of microRNA expression profiles identifies novel biomarkers for hepatocellular carcinoma prognosis.
Wang Z, Ding Q, Li Y, Liu Q, Wu W, Wu L, Yu H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Nov;37(11):14779-14787
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Nov;37(11):14779-14787
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KPNA4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KPNA4. This antibody recognizes human,mouse,rat antigen. The KPNA4 antibody has been validated for the following applications: ELISA, WB analysis.
