Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [4]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-31260 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-31260, RRID:AB_2133841
- Product name
- Rabbit Polyclonal Importin alpha 3/KPNA4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Inhibition of KPNA4 attenuates prostate cancer metastasis.
Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation.
Solomon DA, Stepto A, Au WH, Adachi Y, Diaper DC, Hall R, Rekhi A, Boudi A, Tziortzouda P, Lee YB, Smith B, Bridi JC, Spinelli G, Dearlove J, Humphrey DM, Gallo JM, Troakes C, Fanto M, Soller M, Rogelj B, Parsons RB, Shaw CE, Hortobágyi T, Hirth F
Brain : a journal of neurology 2018 Oct 1;141(10):2908-2924
Brain : a journal of neurology 2018 Oct 1;141(10):2908-2924
Inhibition of KPNA4 attenuates prostate cancer metastasis.
Yang J, Lu C, Wei J, Guo Y, Liu W, Luo L, Fisch G, Li X
Oncogene 2017 May 18;36(20):2868-2878
Oncogene 2017 May 18;36(20):2868-2878
Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation.
Jeong SA, Kim K, Lee JH, Cha JS, Khadka P, Cho HS, Chung IK
Journal of cell science 2015 Jun 15;128(12):2287-301
Journal of cell science 2015 Jun 15;128(12):2287-301
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E. 30 ug BCL-1 whole cell lysate/extract. 7.5 % SDS-PAGE KPNA4 antibody [C3], C-term dilution: 1:1000
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - A. 30 ug Rat2 whole cell lysate/extract 7.5 % SDS-PAGE KPNA4 antibody [C3], C-term dilution: 1:1000
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - Sample (30 ug of whole cell lysate) A: 293T B: HepG2 C: Molt-4 7.5% SDS PAGE diluted at 1:150
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 7.5% SDS PAGE diluted at 1:1000
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - Paraffin-embedded H1299 xenograft, using antibody at 1:500 dilution.