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- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10942-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10942-1-AP, RRID:AB_2205647
- Product name
- TPK1 antibody
- Antibody type
- Polyclonal
- Description
- TPK1 antibody (Cat. #10942-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Chlorogenic Acid Induced Neuroblastoma Cells Differentiation via the ACAT1-TPK1-PDH Pathway.
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Thiamine deficiency contributes to synapse and neural circuit defects.
Thiamine metabolism is critical for regulating correlated growth of dendrite arbors and neuronal somata.
Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells.
Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.
Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells.
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.
Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport.
You S, Wang MJ, Hou ZY, Wang WD, Du TT, Xue NN, Ji M, Chen XG
Pharmaceuticals (Basel, Switzerland) 2023 Jun 14;16(6)
Pharmaceuticals (Basel, Switzerland) 2023 Jun 14;16(6)
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Guarecuco R, Williams RT, Baudrier L, La K, Passarelli MC, Ekizoglu N, Mestanoglu M, Alwaseem H, Rostandy B, Fidelin J, Garcia-Bermudez J, Molina H, Birsoy K
Science advances 2020 Oct;6(41)
Science advances 2020 Oct;6(41)
Thiamine deficiency contributes to synapse and neural circuit defects.
Yu Q, Liu H, Sang S, Chen L, Zhao Y, Wang Y, Zhong C
Biological research 2018 Sep 19;51(1):35
Biological research 2018 Sep 19;51(1):35
Thiamine metabolism is critical for regulating correlated growth of dendrite arbors and neuronal somata.
Liu H, Sang S, Lu Y, Wang Z, Yu X, Zhong C
Scientific reports 2017 Jul 13;7(1):5342
Scientific reports 2017 Jul 13;7(1):5342
Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells.
Srinivasan P, Thrower EC, Loganathan G, Balamurugan AN, Subramanian VS, Gorelick FS, Said HM
PloS one 2015;10(12):e0143575
PloS one 2015;10(12):e0143575
Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.
Tiwana GS, Prevo R, Buffa FM, Yu S, Ebner DV, Howarth A, Folkes LK, Budwal B, Chu KY, Durrant L, Muschel RJ, McKenna WG, Higgins GS
Oncotarget 2015 Mar 20;6(8):5978-89
Oncotarget 2015 Mar 20;6(8):5978-89
Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells.
Liu S, Miriyala S, Keaton MA, Jordan CT, Wiedl C, Clair DK, Moscow JA
PloS one 2014;9(1):e85702
PloS one 2014;9(1):e85702
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 8;111(27):9983-8
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 8;111(27):9983-8
Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.
Sharma A, Madhunapantula SV, Gowda R, Berg A, Neves RI, Robertson GP
The American journal of pathology 2013 Apr;182(4):1151-62
The American journal of pathology 2013 Apr;182(4):1151-62
Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport.
Subramanian VS, Subramanya SB, Tsukamoto H, Said HM
American journal of physiology. Renal physiology 2010 Jul;299(1):F28-34
American journal of physiology. Renal physiology 2010 Jul;299(1):F28-34
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human small intestine tissue were subjected to SDS PAGE followed by western blot with 10942-1-AP(TPK1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TPK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TPK1. This antibody recognizes human,mouse,rat antigen. The TPK1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
