Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN1580460 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-TAR DNA Binding Protein (TARDBP) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- affinity purified antibody
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3H8
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term or -20°C long term.
- Handling
- Avoid repeated freezing and thawing.
Submitted references TDP-43 in aging and Alzheimer's disease - a review.
Wilson AC, Dugger BN, Dickson DW, Wang DS
International journal of clinical and experimental pathology 2011 Jan 30;4(2):147-55
International journal of clinical and experimental pathology 2011 Jan 30;4(2):147-55
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Blots of ABIN1580460 on crude extract of mouse brain nuclear fraction (left lane) and cytoplasmic fraction (right lane) blotted with monoclonal antibody ABIN1580460. There is a strong clear band in the nuclear preparation running at 43 kDa, and a much more minor band in the cytoplasmic fraction.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ABIN1580460 was used to stain a section of formalin fixed adult rat brain, specifically the hippocampus. Hippocampal neuron nuclei are stained strongly. Chicken antibody to GFAP CPCA-GFAP (green) shows the processes of astrocytic glial cells. Nuclei of all cells are revealed with DAPI DNA stain (blue). The TARDP antibody stains neuronal nuclei strongly and the nuclei of some non-neuronal cells much more weakly. Neuronal nuclei therefore look crimson, since they are both red due to the content of TDP43 and blue due to their content of DNA, stained blue with DAPI.