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- Antibody Data
- Antigen structure
- References [10]
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- Western blot [1]
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- Product number
- 66079-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66079-1-Ig, RRID:AB_11183767
- Product name
- Phospho-TDP43 (Ser403/404) antibody
- Antibody type
- Monoclonal
- Description
- Phospho-TDP43 (Ser403/404) antibody (Cat. #66079-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 6B11B12
- Vial size
- 20ul, 100ul
Submitted references KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury.
Sedimentation Assays to Assess the Impact of Posttranslational Modifications on Phase Separation of RNA-Binding Proteins In Vitro and In Cells.
MATR3 P154S knock-in mice do not exhibit motor, muscle or neuropathologic features of ALS.
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.
Influence of APOE genotype in primary age-related tauopathy.
Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis.
Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.
Clinicopathological description of two cases with SQSTM1 gene mutation associated with frontotemporal dementia.
Lai JD, Berlind JE, Fricklas G, Lie C, Urenda JP, Lam K, Sta Maria N, Jacobs R, Yu V, Zhao Z, Ichida JK
Cell stem cell 2024 Apr 4;31(4):519-536.e8
Cell stem cell 2024 Apr 4;31(4):519-536.e8
Sedimentation Assays to Assess the Impact of Posttranslational Modifications on Phase Separation of RNA-Binding Proteins In Vitro and In Cells.
Gruijs da Silva LA, Dormann D
Methods in molecular biology (Clifton, N.J.) 2023;2563:325-339
Methods in molecular biology (Clifton, N.J.) 2023;2563:325-339
MATR3 P154S knock-in mice do not exhibit motor, muscle or neuropathologic features of ALS.
Dominick M, Houchins N, Venugopal V, Zuberi AR, Lutz CM, Meechooveet B, Van Keuren-Jensen K, Bowser R, Medina DX
Biochemical and biophysical research communications 2023 Feb 19;645:164-172
Biochemical and biophysical research communications 2023 Feb 19;645:164-172
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, Perez J, Couto A, Lai J, Li Y, Alworth SV, Hendricks E, Wang Y, Zlokovic BV, Dickman DK, Parker JA, Zarnescu DC, Gao FB, Ichida JK
Cell 2023 Feb 16;186(4):786-802.e28
Cell 2023 Feb 16;186(4):786-802.e28
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
Zambusi A, Novoselc KT, Hutten S, Kalpazidou S, Koupourtidou C, Schieweck R, Aschenbroich S, Silva L, Yazgili AS, van Bebber F, Schmid B, Möller G, Tritscher C, Stigloher C, Delbridge C, Sirko S, Günes ZI, Liebscher S, Schlegel J, Aliee H, Theis F, Meiners S, Kiebler M, Dormann D, Ninkovic J
Nature neuroscience 2022 Dec;25(12):1608-1625
Nature neuroscience 2022 Dec;25(12):1608-1625
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.
Rojas-Prats E, Martinez-Gonzalez L, Gonzalo-Consuegra C, Liachko NF, Perez C, Ramírez D, Kraemer BC, Martin-Requero Á, Perez DI, Gil C, de Lago E, Martinez A
European journal of medicinal chemistry 2021 Jan 15;210:112968
European journal of medicinal chemistry 2021 Jan 15;210:112968
Influence of APOE genotype in primary age-related tauopathy.
Robinson AC, Davidson YS, Roncaroli F, Minshull J, Tinkler P, Horan MA, Payton A, Pendleton N, Mann DMA
Acta neuropathologica communications 2020 Dec 7;8(1):215
Acta neuropathologica communications 2020 Dec 7;8(1):215
Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis.
Ng JSW, Hanspal MA, Matharu NS, Barros TP, Esbjörner EK, Wilson MR, Yerbury JJ, Dobson CM, Kumita JR
Biochemistry 2019 Oct 1;58(39):4086-4095
Biochemistry 2019 Oct 1;58(39):4086-4095
Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.
Chang JC, Morton DB
PloS one 2017;12(7):e0180828
PloS one 2017;12(7):e0180828
Clinicopathological description of two cases with SQSTM1 gene mutation associated with frontotemporal dementia.
Kovacs GG, van der Zee J, Hort J, Kristoferitsch W, Leitha T, Höftberger R, Ströbel T, Van Broeckhoven C, Matej R
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Feb;36(1):27-38
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Feb;36(1):27-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The phospho(403/404)-TDP43 antibody from Proteintech is a mouse monoclonal antibody to a peptide of human phospho(403/404)-TDP43. This antibody recognizes human antigen. The phospho(403/404)-TDP43 antibody has been validated for the following applications: ELISA, WB analysis.
