Antibody data
- Antibody Data
- Antigen structure
- References [49]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 22309-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22309-1-AP, RRID:AB_11182943
- Product name
- Phospho-TDP43 (Ser409/410) antibody
- Antibody type
- Polyclonal
- Description
- Phospho-TDP43 (Ser409/410) antibody (Cat. #22309-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 100ul
Submitted references TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Clinico-pathological comparison of patients with autopsy-confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology.
Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord.
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.
CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.
Neuroinflammation is highest in areas of disease progression in semantic dementia.
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP.
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Increasing Brain Permeability of PHA-767491, a Cell Division Cycle 7 Kinase Inhibitor, with Biodegradable Polymeric Nanoparticles.
Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice.
Repetitive Traumatic Brain Injury Is Associated With TDP-43 Alterations, Neurodegeneration, and Glial Activation in Mice.
Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus.
Tideglusib, a Non-ATP Competitive Inhibitor of GSK-3β as a Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis.
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation.
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Spinal Cord and Motor Neuron TDP-43 Pathology in a Sporadic Inclusion Body Myositis Patient.
Cytoplasmic mislocalization and mitochondrial colocalization of TDP-43 are common features between normal aged and young mice.
Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment.
Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment.
Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.
A robust TDP-43 knock-in mouse model of ALS.
Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS.
Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets.
Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis.
A clinicopathological study of ALS with L126S mutation in the SOD1 gene presenting with isolated inferior olivary hypertrophy.
Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression.
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis.
Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.
Association between TDP-43 and mitochondria in inclusion body myositis.
Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial.
Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.
Variably protease-sensitive prionopathy mimicking frontotemporal dementia.
Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis.
Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.
Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease.
Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis.
Reappraisal of TDP-43 pathology in FTLD-U subtypes.
In vitro prion-like behaviour of TDP-43 in ALS.
Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.
PABPN1 suppresses TDP-43 toxicity in ALS disease models.
An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.
ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation.
Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration.
β-N-methylamino-L-alanine induces changes in both GSK3 and TDP-43 in human neuroblastoma.
Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis.
An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43.
Xie M, Liu YU, Zhao S, Zhang L, Bosco DB, Pang YP, Zhong J, Sheth U, Martens YA, Zhao N, Liu CC, Zhuang Y, Wang L, Dickson DW, Mattson MP, Bu G, Wu LJ
Nature neuroscience 2022 Jan;25(1):26-38
Nature neuroscience 2022 Jan;25(1):26-38
Clinico-pathological comparison of patients with autopsy-confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology.
Chatterjee A, Hirsch-Reinshagen V, Moussavi SA, Ducharme B, Mackenzie IR, Hsiung GR
Alzheimer's & dementia (Amsterdam, Netherlands) 2021;13(1):e12189
Alzheimer's & dementia (Amsterdam, Netherlands) 2021;13(1):e12189
Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord.
Cathcart SJ, Appel SH, Peterson LE, Greene EP, Powell SZ, Arumanayagam AS, Rivera AL, Cykowski MD
Journal of neuropathology and experimental neurology 2021 Sep 10;80(8):754-763
Journal of neuropathology and experimental neurology 2021 Sep 10;80(8):754-763
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.
Altman T, Ionescu A, Ibraheem A, Priesmann D, Gradus-Pery T, Farberov L, Alexandra G, Shelestovich N, Dafinca R, Shomron N, Rage F, Talbot K, Ward ME, Dori A, Krüger M, Perlson E
Nature communications 2021 Nov 25;12(1):6914
Nature communications 2021 Nov 25;12(1):6914
CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.
Tosat-Bitrián C, Avis-Bodas A, Porras G, Borrego-Hernández D, García-Redondo A, Martín-Requero A, Palomo V
Nanomaterials (Basel, Switzerland) 2021 Mar 9;11(3)
Nanomaterials (Basel, Switzerland) 2021 Mar 9;11(3)
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.
Kahriman A, Bouley J, Smith TW, Bosco DA, Woerman AL, Henninger N
Acta neuropathologica communications 2021 Jun 29;9(1):118
Acta neuropathologica communications 2021 Jun 29;9(1):118
Neuroinflammation is highest in areas of disease progression in semantic dementia.
Pascual B, Funk Q, Zanotti-Fregonara P, Cykowski MD, Veronese M, Rockers E, Bradbury K, Yu M, Nakawah MO, Román GC, Schulz PE, Arumanayagam AS, Beers D, Faridar A, Fujita M, Appel SH, Masdeu JC
Brain : a journal of neurology 2021 Jun 22;144(5):1565-1575
Brain : a journal of neurology 2021 Jun 22;144(5):1565-1575
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP.
Feneberg E, Charles PD, Finelli MJ, Scott C, Kessler BM, Fischer R, Ansorge O, Gray E, Talbot K, Turner MR
Brain pathology (Zurich, Switzerland) 2021 Jul;31(4):e12923
Brain pathology (Zurich, Switzerland) 2021 Jul;31(4):e12923
Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Sieverding K, Ulmer J, Bruno C, Satoh T, Tsao W, Freischmidt A, Akira S, Wong PC, Ludolph AC, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH
Experimental neurology 2021 Jan;335:113496
Experimental neurology 2021 Jan;335:113496
Increasing Brain Permeability of PHA-767491, a Cell Division Cycle 7 Kinase Inhibitor, with Biodegradable Polymeric Nanoparticles.
Rojas-Prats E, Tosat-Bitrián C, Martínez-González L, Nozal V, Pérez DI, Martínez A
Pharmaceutics 2021 Jan 28;13(2)
Pharmaceutics 2021 Jan 28;13(2)
Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice.
Ding X, Xiang Z, Qin C, Chen Y, Tian H, Meng L, Xia D, Liu H, Song J, Fu J, Ma M, Wang X
Acta neuropathologica communications 2021 Jan 18;9(1):15
Acta neuropathologica communications 2021 Jan 18;9(1):15
Repetitive Traumatic Brain Injury Is Associated With TDP-43 Alterations, Neurodegeneration, and Glial Activation in Mice.
Rajič Bumber J, Pilipović K, Janković T, Dolenec P, Gržeta N, Križ J, Župan G
Journal of neuropathology and experimental neurology 2021 Jan 1;80(1):2-14
Journal of neuropathology and experimental neurology 2021 Jan 1;80(1):2-14
Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á
Journal of neurochemistry 2021 Feb;156(3):379-390
Journal of neurochemistry 2021 Feb;156(3):379-390
Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus.
Mitani TT, Beck G, Kido K, Yamashita R, Yonenobu Y, Ogawa T, Saeki C, Okuno T, Nagano S, Morii E, Hasegawa M, Saito Y, Murayama S, Mochizuki H
Neuropathology : official journal of the Japanese Society of Neuropathology 2021 Aug;41(4):324-331
Neuropathology : official journal of the Japanese Society of Neuropathology 2021 Aug;41(4):324-331
Tideglusib, a Non-ATP Competitive Inhibitor of GSK-3β as a Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis.
Martínez-González L, Gonzalo-Consuegra C, Gómez-Almería M, Porras G, de Lago E, Martín-Requero Á, Martínez A
International journal of molecular sciences 2021 Aug 20;22(16)
International journal of molecular sciences 2021 Aug 20;22(16)
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation.
Fernandes N, Nero L, Lyons SM, Ivanov P, Mittelmeier TM, Bolger TA, Buchan JR
Biomolecules 2020 Sep 25;10(10)
Biomolecules 2020 Sep 25;10(10)
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Gabellieri E, Capotosti F, Molette J, Sreenivasachary N, Mueller A, Berndt M, Schieferstein H, Juergens T, Varisco Y, Oden F, Schmitt-Willich H, Hickman D, Dinkelborg L, Stephens A, Pfeifer A, Kroth H
European journal of medicinal chemistry 2020 Oct 15;204:112615
European journal of medicinal chemistry 2020 Oct 15;204:112615
Spinal Cord and Motor Neuron TDP-43 Pathology in a Sporadic Inclusion Body Myositis Patient.
Cathcart SJ, Greene EP, Powell SZ, Arumanayagam AS, Rivera AL, Tawil R, Appel SH, Cykowski MD
Journal of neuropathology and experimental neurology 2020 Oct 1;79(10):1130-1133
Journal of neuropathology and experimental neurology 2020 Oct 1;79(10):1130-1133
Cytoplasmic mislocalization and mitochondrial colocalization of TDP-43 are common features between normal aged and young mice.
Termsarasab P, Thammongkolchai T, Gao J, Wang L, Liang J, Wang X
Experimental biology and medicine (Maywood, N.J.) 2020 Nov;245(17):1584-1593
Experimental biology and medicine (Maywood, N.J.) 2020 Nov;245(17):1584-1593
Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment.
Martínez-González L, Rodríguez-Cueto C, Cabezudo D, Bartolomé F, Andrés-Benito P, Ferrer I, Gil C, Martín-Requero Á, Fernández-Ruiz J, Martínez A, de Lago E
Scientific reports 2020 Mar 10;10(1):4449
Scientific reports 2020 Mar 10;10(1):4449
Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment.
Wang Y, Liu Y, Nham A, Sherbaf A, Quach D, Yahya E, Ranburger D, Bi X, Baudry M
Science advances 2020 Jul;6(27)
Science advances 2020 Jul;6(27)
Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.
Gregory JM, Livesey MR, McDade K, Selvaraj BT, Barton SK, Chandran S, Smith C
The Journal of pathology 2020 Jan;250(1):67-78
The Journal of pathology 2020 Jan;250(1):67-78
A robust TDP-43 knock-in mouse model of ALS.
Huang SL, Wu LS, Lee M, Chang CW, Cheng WC, Fang YS, Chen YR, Cheng PL, Shen CJ
Acta neuropathologica communications 2020 Jan 21;8(1):3
Acta neuropathologica communications 2020 Jan 21;8(1):3
Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS.
Gregory JM, McDade K, Bak TH, Pal S, Chandran S, Smith C, Abrahams S
Journal of neurology, neurosurgery, and psychiatry 2020 Feb;91(2):149-157
Journal of neurology, neurosurgery, and psychiatry 2020 Feb;91(2):149-157
Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets.
Sage JM, Hall L, McVey A, Barohn RJ, Statland JM, Jawdat O, Dimachkie MM, Agbas A
Journal of visualized experiments : JoVE 2020 Feb 10;(156)
Journal of visualized experiments : JoVE 2020 Feb 10;(156)
Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis.
Gregory JM, Elliott E, McDade K, Bak T, Pal S, Chandran S, Abrahams S, Smith C
Neuropathology and applied neurobiology 2020 Apr;46(3):255-263
Neuropathology and applied neurobiology 2020 Apr;46(3):255-263
A clinicopathological study of ALS with L126S mutation in the SOD1 gene presenting with isolated inferior olivary hypertrophy.
Hideshima M, Beck G, Yamadera M, Motoyama Y, Ikenaka K, Kakuda K, Tsuda H, Nagano S, Fujimura H, Morii E, Murayama S, Mochizuki H
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Apr;40(2):191-195
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Apr;40(2):191-195
Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression.
Regalado-Reyes M, Furcila D, Hernández F, Ávila J, DeFelipe J, León-Espinosa G
Journal of Alzheimer's disease : JAD 2019;69(1):277-288
Journal of Alzheimer's disease : JAD 2019;69(1):277-288
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT
Acta neuropathologica communications 2019 Oct 30;7(1):158
Acta neuropathologica communications 2019 Oct 30;7(1):158
Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis.
Ng JSW, Hanspal MA, Matharu NS, Barros TP, Esbjörner EK, Wilson MR, Yerbury JJ, Dobson CM, Kumita JR
Biochemistry 2019 Oct 1;58(39):4086-4095
Biochemistry 2019 Oct 1;58(39):4086-4095
Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.
Chen Y, Cohen TJ
The Journal of biological chemistry 2019 Mar 8;294(10):3696-3706
The Journal of biological chemistry 2019 Mar 8;294(10):3696-3706
Association between TDP-43 and mitochondria in inclusion body myositis.
Huntley ML, Gao J, Termsarasab P, Wang L, Zeng S, Thammongkolchai T, Liu Y, Cohen ML, Wang X
Laboratory investigation; a journal of technical methods and pathology 2019 Jul;99(7):1041-1048
Laboratory investigation; a journal of technical methods and pathology 2019 Jul;99(7):1041-1048
Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial.
Statland JM, Moore D, Wang Y, Walsh M, Mozaffar T, Elman L, Nations SP, Mitsumoto H, Fernandes JA, Saperstein D, Hayat G, Herbelin L, Karam C, Katz J, Wilkins HM, Agbas A, Swerdlow RH, Santella RM, Dimachkie MM, Barohn RJ, Rasagiline Investigators of the Muscle Study Group and Western ALS Consortium.
Muscle & nerve 2019 Feb;59(2):201-207
Muscle & nerve 2019 Feb;59(2):201-207
Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.
Posa D, Martínez-González L, Bartolomé F, Nagaraj S, Porras G, Martínez A, Martín-Requero Á
Molecular neurobiology 2019 Apr;56(4):2424-2432
Molecular neurobiology 2019 Apr;56(4):2424-2432
Variably protease-sensitive prionopathy mimicking frontotemporal dementia.
Aizpurua M, Selvackadunco S, Yull H, Kipps CM, Ironside JW, Bodi I
Neuropathology : official journal of the Japanese Society of Neuropathology 2019 Apr;39(2):135-140
Neuropathology : official journal of the Japanese Society of Neuropathology 2019 Apr;39(2):135-140
Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis.
Henstridge CM, Sideris DI, Carroll E, Rotariu S, Salomonsson S, Tzioras M, McKenzie CA, Smith C, von Arnim CAF, Ludolph AC, Lulé D, Leighton D, Warner J, Cleary E, Newton J, Swingler R, Chandran S, Gillingwater TH, Abrahams S, Spires-Jones TL
Acta neuropathologica 2018 Feb;135(2):213-226
Acta neuropathologica 2018 Feb;135(2):213-226
Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.
Cykowski MD, Powell SZ, Appel JW, Arumanayagam AS, Rivera AL, Appel SH
Acta neuropathologica communications 2018 Apr 13;6(1):28
Acta neuropathologica communications 2018 Apr 13;6(1):28
Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease.
Wilhite R, Sage JM, Bouzid A, Primavera T, Agbas A
Future science OA 2017 Nov;3(4):FSO238
Future science OA 2017 Nov;3(4):FSO238
Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis.
Cykowski MD, Powell SZ, Peterson LE, Appel JW, Rivera AL, Takei H, Chang E, Appel SH
Journal of neuropathology and experimental neurology 2017 May 1;76(5):402-413
Journal of neuropathology and experimental neurology 2017 May 1;76(5):402-413
Reappraisal of TDP-43 pathology in FTLD-U subtypes.
Mackenzie IR, Neumann M
Acta neuropathologica 2017 Jul;134(1):79-96
Acta neuropathologica 2017 Jul;134(1):79-96
In vitro prion-like behaviour of TDP-43 in ALS.
Smethurst P, Newcombe J, Troakes C, Simone R, Chen YR, Patani R, Sidle K
Neurobiology of disease 2016 Dec;96:236-247
Neurobiology of disease 2016 Dec;96:236-247
Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.
Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á
Molecular neurodegeneration 2016 Apr 30;11(1):36
Molecular neurodegeneration 2016 Apr 30;11(1):36
PABPN1 suppresses TDP-43 toxicity in ALS disease models.
Chou CC, Alexeeva OM, Yamada S, Pribadi A, Zhang Y, Mo B, Williams KR, Zarnescu DC, Rossoll W
Human molecular genetics 2015 Sep 15;24(18):5154-73
Human molecular genetics 2015 Sep 15;24(18):5154-73
An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.
Okamoto K, Fujita Y, Hoshino E, Tamura Y, Fukuda T, Hasegawa M, Takatama M
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Oct;35(5):462-8
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Oct;35(5):462-8
ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation.
King A, Troakes C, Smith B, Nolan M, Curran O, Vance C, Shaw CE, Al-Sarraj S
Acta neuropathologica communications 2015 Oct 9;3:62
Acta neuropathologica communications 2015 Oct 9;3:62
Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration.
Bit-Ivan EN, Lee KH, Gitelman D, Weintraub S, Mesulam M, Rademakers R, Isaacs AM, Hatanpaa KJ, White CL 3rd, Mao Q, Akman O, DiMauro S, Bigio EH
Neuropathology and applied neurobiology 2014 Oct;40(6):778-82
Neuropathology and applied neurobiology 2014 Oct;40(6):778-82
β-N-methylamino-L-alanine induces changes in both GSK3 and TDP-43 in human neuroblastoma.
Muñoz-Saez E, de Munck E, Arahuetes RM, Solas MT, Martínez AM, Miguel BG
The Journal of toxicological sciences 2013;38(3):425-30
The Journal of toxicological sciences 2013;38(3):425-30
Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis.
Dobson-Stone C, Luty AA, Thompson EM, Blumbergs P, Brooks WS, Short CL, Field CD, Panegyres PK, Hecker J, Solski JA, Blair IP, Fullerton JM, Halliday GM, Schofield PR, Kwok JB
Acta neuropathologica 2013 Apr;125(4):523-33
Acta neuropathologica 2013 Apr;125(4):523-33
An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43.
Pelletier S, Gingras S, Howell S, Vogel P, Ihle JN
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 21;32(47):16560-73
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 21;32(47):16560-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The phospho(409/410)-TDP43 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human phospho(409/410)-TDP43. This antibody recognizes human, mouse antigen. The phospho(409/410)-TDP43 antibody has been validated for the following applications: ELISA, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using TARDBP antibody 22309-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line