ABIN500883

antibody from antibodies-online

Targeting: TARDBP ALS10, TDP-43

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN500883

Provider

antibodies-online

Product name

anti-TAR DNA Binding Protein (TARDBP) (Center) antibody

Antibody type

Polyclonal

Antigen

TDP43 antibody was raised against a 18 amino acid peptide from near the center of humanTDP43.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM
Science (New York, N.Y.) 2006 Oct 6;314(5796):130-3

---

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.

Buratti E, Dörk T, Zuccato E, Pagani F, Romano M, Baralle FE
The EMBO journal 2001 Apr 2;20(7):1774-84

---

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

Ou SH, Wu F, Harrich D, García-Martínez LF, Gaynor RB
Journal of virology 1995 Jun;69(6):3584-96

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of TDP43 in L1210 cell lysate with AP30865PU-N at (A) 0.5, (B) 1 and (C) 2 ?g/ml.

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunocytochemistry of TDP43 in HeLa cells with AP30865PU-N at 5 ?g/ml.