Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN500883 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-TAR DNA Binding Protein (TARDBP) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- TDP43 antibody was raised against a 18 amino acid peptide from near the center of humanTDP43.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.
Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM
Science (New York, N.Y.) 2006 Oct 6;314(5796):130-3
Science (New York, N.Y.) 2006 Oct 6;314(5796):130-3
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.
Buratti E, Dörk T, Zuccato E, Pagani F, Romano M, Baralle FE
The EMBO journal 2001 Apr 2;20(7):1774-84
The EMBO journal 2001 Apr 2;20(7):1774-84
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.
Ou SH, Wu F, Harrich D, García-Martínez LF, Gaynor RB
Journal of virology 1995 Jun;69(6):3584-96
Journal of virology 1995 Jun;69(6):3584-96
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of TDP43 in L1210 cell lysate with AP30865PU-N at (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of TDP43 in HeLa cells with AP30865PU-N at 5 ?g/ml.