ABIN1003253

antibody from antibodies-online

Targeting: TARDBP ALS10, TDP-43

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1003253

Provider

antibodies-online

Product name

anti-TAR DNA Binding Protein (TARDBP) (Internal Region) antibody

Antibody type

Polyclonal

Antigen

TDP43 antibody was raised in rabbits against an 18 amino acid peptide from near the center of human TDP43.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100 µg

Storage

-20°C Shipping Temperature: 4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.

References

Submitted references

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM
Science (New York, N.Y.) 2006 Oct 6;314(5796):130-3

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Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.

Buratti E, Dörk T, Zuccato E, Pagani F, Romano M, Baralle FE
The EMBO journal 2001 Apr 2;20(7):1774-84

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Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

Ou SH, Wu F, Harrich D, García-Martínez LF, Gaynor RB
Journal of virology 1995 Jun;69(6):3584-96