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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- 308803 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#308803, RRID:AB_314735
- Product name
- PE anti-human CD210 (IL-10 R)
- Antibody type
- Monoclonal
- Antigen
- CD210 (IL-10 R)
- Description
- CD210, also known as the IL-10 receptor, is a 90-110 kD protein expressed on T cells, B cells, NK cells, monocytes and macrophages. CD210 belongs to the class II cytokine receptor family which includes the IFN-γ receptor (CDw119), the IFN-α/β receptor (CD118) and tissue factor (CD142). The IL-10 receptor is involved in signal transduction by inducing phosphorylation of STAT1a and STAT3 and by inducing activation of Jak1 and Tyk.
- Reactivity
- Human, Simian
- Host
- Rat
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Role for IL-10 in inducing functional impairment of monocytes upon TLR4 ligation in patients with chronic HCV infections.
T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible.
Liu BS, Groothuismink ZM, Janssen HL, Boonstra A
Journal of leukocyte biology 2011 Jun;89(6):981-8
Journal of leukocyte biology 2011 Jun;89(6):981-8
T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible.
Huang YH, Zozulya AL, Weidenfeller C, Schwab N, Wiendl H
Journal of leukocyte biology 2009 Aug;86(2):273-81
Journal of leukocyte biology 2009 Aug;86(2):273-81
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with 3F9 PE
- Conjugate
- Yellow dye
