Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [6]
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Validation data
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- Product number
- NBP1-87720 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-87720, RRID:AB_11013077
- Product name
- Rabbit Polyclonal DNA Ligase III Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human DNA Ligase III antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF.
Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.
Tadi SK, Tellier-Lebègue C, Nemoz C, Drevet P, Audebert S, Roy S, Meek K, Charbonnier JB, Modesti M
Cell reports 2016 Oct 4;17(2):541-555
Cell reports 2016 Oct 4;17(2):541-555
Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.
Fan J, Li L, Small D, Rassool F
Blood 2010 Dec 9;116(24):5298-305
Blood 2010 Dec 9;116(24):5298-305
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNA Ligase III Antibody [NBP1-87720] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNA Ligase III Antibody [NBP1-87720] - Analysis in human cell line A-549.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human cerebellum shows moderate nuclear positivity in Purkinje cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human prostate shows moderate nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human cerebral cortex shows strong nuclear positivity in neurons.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human skeletal muscle shows weak nuclear positivity in myocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Ligase III Antibody [NBP1-87720] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.