Antibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Western blot [1]
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- Product number
- BS8361 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PNKP polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PNKP.
- Description
- Bifunctional polynucleotide phosphatase/kinase (PNK), also referred to as polynucleotide kinase-3'-phosphatase, is a member of the DNA 3£ª phosphatase family. PNK is the protein expressed by the gene PNKP and contains a 3'-phosphatase domain with similarity to L-2-haloacid dehalogenases and a reported ATP binding site. PNK is a nuclear protein that is involved in DNA repair following damage caused by radiation or oxidation. The protein catalyzes the phosphorylation of DNA at the hydroxy termini but can also dephosphorylate its 3£ª-phosphate termini. The highest levels of expression of PNK occur in testis, pancreas, spleen, kidney and heart.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of PNKP polyclonal antibody