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Western blot
Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA046537 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA046537, RRID:AB_2679689
- Product name
- Anti-MECOM
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MECOM, Gene description: MDS1 and EVI1 complex locus, Alternative Gene Names: EVI1, MDS1, MDS1-EVI1, PRDM3, Validated applications: WB, IHC, ICC, ChIP, Uniprot ID: Q03112, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis
Downregulation of EVI1 Expression Inhibits Cell Proliferation and Induces Apoptosis in Hilar Cholangiocarcinoma via the PTEN/AKT Signalling Pathway.
Chen Z, Li P, Shen L, Jiang X
Oncology Reports 2023;50(5)
Oncology Reports 2023;50(5)
Downregulation of EVI1 Expression Inhibits Cell Proliferation and Induces Apoptosis in Hilar Cholangiocarcinoma via the PTEN/AKT Signalling Pathway.
Zhang XM, Liu ZL, Qiu B, Xu YF, Pan C, Zhang ZL
Journal of Cancer 2020;11(6):1412-1423
Journal of Cancer 2020;11(6):1412-1423
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Supportive validation
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- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-MECOM (HPA046537, Lot 000004628) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
