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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS7328 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- POLI polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human POLI.
- Description
- Mammalian Pol êò owns an unusual combination of properties: it is stimulated by Mn2+ ions, can bypass some DNA lesions and misincorporates ¡ùG¡ì opposite template ¡ùT¡ì more frequently than incorporates the correct ¡ùA.¡ì [PMID:21304950] It also was shown to possess dRP lyase activity. In addition, Pol êò is much more efficient in the presence of Mn2+ in comparison to Mg2+. [PMID: 17609217]. It has been proposed that POLI involves in immunoglobulin somatic hypermutation (SHM), bypass of deaminated cytosines, several adducts of the purine bases. DNA strand crosslinks and is involved in DNA repair under oxidative stress. [PMID:15199127]
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of POLI polyclonal antibody
