Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
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Validation data
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- Product number
- ABIN564869 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Polymerase (DNA Directed) iota (POLI) (AA 616-715), (partial) antibody
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 616-715, partial
- Isotype
- IgG
- Antibody clone number
- 8G9
- Vial size
- 50 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Handling
- Aliquot to avoid repeated freezing and thawing.
Submitted references Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication.
Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.
Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations.
Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T
Molecular and cellular biology 2015 Feb;35(4):699-715
Molecular and cellular biology 2015 Feb;35(4):699-715
Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.
Takezawa J, Ishimi Y, Aiba N, Yamada K
Journal of nucleic acids 2010 Dec 1;2010:750296
Journal of nucleic acids 2010 Dec 1;2010:750296
Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations.
Wang Y, Woodgate R, McManus TP, Mead S, McCormick JJ, Maher VM
Cancer research 2007 Apr 1;67(7):3018-26
Cancer research 2007 Apr 1;67(7):3018-26
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA