PA5-52963

antibody from Invitrogen Antibodies

Targeting: NUDT1 MTH1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-52963

Provider

Invitrogen Antibodies

Product name

MTH1 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: RWNGFGGKVQ EGETIEDGAR RELQEESGLT VDALHKVGQI VFEFVGEPEL MDVHVFCTDS IQGTPVESDE MRPCWFQLDQ IPFKDMWPDD SYWFPLLLQK KKFHGYFKFQ GQDTILDYTL

Concentration

0.1 mg/mL

References

Submitted references

Hepatitis B Virus X Protein Increases 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine (8-Oxodg) Level via Repressing MTH1/ MTH2 Expression in Hepatocytes.

Lin YT, Liu W, He Y, Wu YL, Chen WN, Lin XJ, Lin X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(1):80-96

Western blot

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot analysis of MTH1 in human cell line A-549 using a MTH1 Polyclonal Antibody (Product # PA5-52963).

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot analysis of MTH1 in control (vector only transfected HEK293T lysate) and NUDT1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a MTH1 Polyclonal Antibody (Product # PA5-52963).

Immunocytochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of MTH1 in human cell line U-2 OS shows positivity in cytoplasm. Samples were probed using a MTH1 Polyclonal Antibody (Product # PA5-52963).

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of MTH1 in human testis tissue shows moderate cytoplasmic positivity in cells in seminiferous ducts. Samples were probed using a MTH1 Polyclonal Antibody (Product # PA5-52963).