Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- BS9166 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- GBDR1 (R126) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 90-138 of Human GBDR1.
- Description
- GBDR1 (glialblastoma cell differentiation-related protein 1), also known as UBAC1 (ubiquitin-associated domain-containing protein 1), KPC2 or UBADC1, is a 405 amino acid protein that localizes to the cytoplasm and contains one ubiquitin-like domain, one STI1 domain and two UBA domains. Expressed ubiquitously with highest expression in heart and skeletal muscle, GBDR1 functions as a non-catalytic subunit of the KPC E3 ubiquitin-protein ligase complex, of which RNF123 is the catalytic subunit. Existing as a critical component of the KPC complex, GBDR1 is essential for the ubiquitination and proteasome-mediated degradation of p27 during the G1 phase of the cell cycle. The gene encoding GBDR1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
No comments: Submit comment
No validations: Submit validation data