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- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21147-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21147-1-AP, RRID:AB_10732604
- Product name
- TACO1/CCDC44 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TACO1/CCDC44 antibody (Cat. #21147-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression.
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria.
PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis.
Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.
Fidelity of translation initiation is required for coordinated respiratory complex assembly.
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.
Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Kramer NJ, Prakash G, Isaac RS, Choquet K, Soto I, Petrova B, Merens HE, Kanarek N, Churchman LS
Nature cell biology 2023 Nov;25(11):1575-1589
Nature cell biology 2023 Nov;25(11):1575-1589
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria.
Speck SL, Bhatt DP, Zhang Q, Adak S, Yin L, Dong G, Feng C, Zhang W, Ben Major M, Wei X, Semenkovich CF
Cell reports 2023 Nov 28;42(11):113389
Cell reports 2023 Nov 28;42(11):113389
PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis.
Sun Q, Shi L, Li S, Li J, Zhang R, Huang X, Shao Y, Feng Z, Peng Y, Yang Z, Liu J, Liu H, Long J
Free radical biology & medicine 2023 Aug 20;205:13-24
Free radical biology & medicine 2023 Aug 20;205:13-24
Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.
Yokokawa T, Mori R, Suga T, Isaka T, Hayashi T, Fujita S
Biochemical and biophysical research communications 2020 Jun 18;527(1):146-152
Biochemical and biophysical research communications 2020 Jun 18;527(1):146-152
Fidelity of translation initiation is required for coordinated respiratory complex assembly.
Rudler DL, Hughes LA, Perks KL, Richman TR, Kuznetsova I, Ermer JA, Abudulai LN, Shearwood AJ, Viola HM, Hool LC, Siira SJ, Rackham O, Filipovska A
Science advances 2019 Dec;5(12):eaay2118
Science advances 2019 Dec;5(12):eaay2118
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.
Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O
The EMBO journal 2019 Dec 16;38(24):e102155
The EMBO journal 2019 Dec 16;38(24):e102155
Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.
Yokokawa T, Kido K, Suga T, Isaka T, Hayashi T, Fujita S
Physiological reports 2018 Oct;6(20):e13893
Physiological reports 2018 Oct;6(20):e13893
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.
Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A
Nature communications 2016 Jun 20;7:11884
Nature communications 2016 Jun 20;7:11884
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD
Cell 2014 Jul 31;158(3):607-19
Cell 2014 Jul 31;158(3):607-19
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 21147-1-AP( CCDC44 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21147-1-AP(CCDC44 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TACO1/CCDC44 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TACO1/CCDC44. This antibody recognizes human,mouse,rat antigen. The TACO1/CCDC44 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
